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Published on March 28, 2024
A study to be presented at the American College of Cardiology’s Annual Scientific Session found that young adults who were prescribed stimulant medications for attention deficit/hyperactivity disorder (ADHD) were more like to develop cardiomyopathy—a weakened heart muscle—compared with young adults who were not prescribed them. In particular, the study showed…
Published on November 22, 2023
Results from a large study carried out in Sweden show that long-term use of attention-deficit/hyperactivity disorder (ADHD) medication can increase cardiovascular disease (CVD) risk. Zheng Chang, a group leader at the Karolinska Institutet in Stockholm, and colleagues found that for every year of ADHD medication use CVD risk increased by…
Published on February 10, 2023
Researchers have identified 27 genetic risk loci for attention-deficit hyperactivity disorder (ADHD) and provided a window into how it relates to other psychiatric conditions. The genome-wide analyses revealed 21 new loci linked with the neurodevelopmental disorder and found that it was influenced by thousands of genetic variants. The vast majority…
Published on December 8, 2022
Being genetically predisposed to attention-deficit/hyperactivity disorder (ADHD) could increase the risk of Alzheimer’s disease in later life, research suggests. The study revealed that well-established ADHD biomarkers were collectively associated with cognitive declines, particularly in memory, among previously unaffected older adults. Cognitive decline was most common in those displaying amyloid (A)β…
Published on November 23, 2022
Results from a study led by Yale School of Medicine show that functional magnetic resonance imaging (fMRI) scans could help diagnose attention-deficit/hyperactivity disorder (ADHD) in children more effectively than current methods. Statistics suggest that ADHD is one of the most common neurodevelopmental disorders, impacting around six million under 18-year olds…
Published on November 16, 2022
New research from investigators at the National Institutes of Health (NIH) has revealed differences in the gene activity in the brains of people identified as having attention deficit hyperactivity disorder (ADHD). The study, conducted by scientists at NIH’s National Human Genome Research Institute (NHGRI) found that people with ADHD had…
Published on July 14, 2022
Researchers at the Children’s Hospital of Philadelphia’s (CHOP) Center for Applied Genomics (CAG) have developed an algorithm using existing electronic health records (EHRs) is able to distinguish patients with attention deficit/hyperactivity disorder (ADHD) alone from other related conditions. The researchers hope the new tool can be applied in broader clinical…
Published on April 8, 2022
A new study led by researchers from the University of Michigan demonstrate that mice with a variant associated with Attention deficit hyperactivity disorder (ADHD) adopt an inattentive phenotype similar to that seen in humans. Results of the study, published in The Journal of Neuroscience, indicate that a variant (Val89) in the choline…
Published on September 23, 2020
Research carried out at the Children’s Hospital of Philadelphia suggests that structural genetic variants linked to attention-deficit hyperactivity disorder (ADHD) vary considerably between African Americans and individuals of European origin. The scientists, led Hakon Hakonarson, M.D., Ph.D., a professor at the Perelman School of Medicine at the University of Pennsylvania…
Published on November 27, 2019
People with autism or ADHD share certain rare mutations, according to researchers from iPSYCH in Denmark, the Broad Institute and Harvard. One of the most commonly shared types of mutations were those affecting the microtubule-associated protein 1A gene (MAP1A), which is involved in the formation of nerve cells. According to…
Published on November 29, 2018
A genome-wide association study (GWAS) published this week confirms what the psychiatric community has theorized for decades—that attention deficit/hyperactivity disorder (ADHD) has a large genetic component. A collaborative, global research team has identified the first genetic variants that increase the risk of ADHD. Anita Thapar, Ph.D., professor in the division…
Published on February 7, 2024
Credit: Nathalie Ruaux / wikimedia commons Although not necessarily the father of exposomics, Christopher Wild certainly gave life to the term exposome in the title of his August 2005 paper published in Cancer Epidemiology, Biomarkers & Prevention. Fresh on the heels of the completion of the…
Published on January 11, 2024
Ancient genes predisposing people to multiple sclerosis (MS) may have spread due to the protection they afforded against infectious diseases thousands of years ago. A major migration of sheep and cattle herders 5000 years ago appears to have introduced genes that increased the risk of MS into northern Europe, where…
Published on June 19, 2023
New research by a team of Chinese, Canadian, and U.S. researchers has found that seeding newborn babies who are born via C-section with their mother’s vaginal bacteria improves neurodevelopment in the first months of life. The research, published last week in the journal Cell Host & Microbe, suggests this can…
Published on May 19, 2023
Genes expressed in the brain before birth may affect development of a range of mental illnesses during childhood, according to new research. A Massachusetts General Hospital (MGH) team has found a new gene “set” that helps predict risk for several neurodevelopmental disorders, including autism, ADHD, Tourette syndrome, and depression. The…