The number one thing most people fear as they age is developing dementia. As the world’s population becomes increasingly older, this is a growing public health issue too. The World Health Organization estimates that 55 million people already have dementia worldwide. With a global market estimated to reach $13 billion…

Research led by two teams from the University of California San Francisco (UCSF) and a team from the University of Queensland, Australia, has identified a blood factor as the common denominator behind rejuvenation of the brain through young blood transfusion, a longevity hormone and exercise. In a trio of papers…

Researchers say they have mapped the gene expression of each individual brain cell during aging in the fruit fly. Their study (“A Single-Cell Transcriptome Atlas of the Aging Drosophila Brain”), published in Cell, could lead to new insights on the workings of the brain as it ages, according to the…

In a new study, scientists at the University of Rochester Medical Center have demonstrated that it is possible to reverse the age-related decline in the brain’s ability to clear out harmful waste, a process that could have significant implications for treating neurodegenerative diseases like Alzheimer’s and Parkinson’s. Published in Nature…

A multicenter research and development effort led by a team of neurosurgeons and engineers at Michigan Medicine at the University of Michigan (U-M) have developed a screening system call DeepGlioma that employs rapid imaging plus artificial intelligence (AI) to detect brain cancer mutations in under 90 seconds. “This AI-based tool…

Using MRI scans and machine learning, a team led by University College of London (UCL) researchers has identified some risk factors for premature brain aging. They found that worse cardiovascular health at age 36 predicted a higher brain age later in life, while men also tended to have older brains…

A novel technology designed to precisely image aggressive brain cancers and guide treatment is being prepared for a phase 1 trial in glioblastoma, the most common type of brain cancer. The new MRI nanotechnology targets a specific marker, fibroblast activation protein (FAP), that is found in the majority of solid…

New research from investigators at the UC San Francisco Memory and Aging Center, has shown that brain imaging of pathological tau-protein tangles can reliably predict the location of future brain atrophy in Alzheimer’s patients a year or more in advance. The findings may signal a shift away from the heavy…

A score made up of a series of visual measurements taken from images of the retinal blood vessels at the back of the eye can significantly improve stroke prediction, shows new research. The study, led by the Hong Kong Polytechnic University and the University of Melbourne, identified 29 retinal vascular…

The largest study on brain aging shows that not all brain cell types age in the same way, and there may be connections between diet, inflammation, and brain health. The authors believe this study provides a roadmap for how aging may alter brain cell genetic activity. The team, from the…

A genetic predisposition to dyslexia may be associated with specific brain structures that could also predispose to several other conditions, according to a major study involving data from the UK Biobank and 23andMe. Brain structures involved in motor, language-related and visual functions were implicated in dyslexia, a condition that is…

Researchers at the University of California, Los Angeles (UCLA) have identified a promising new blood-based biomarker that could help detect early brain changes linked to cognitive impairment and dementia. The study, published in Alzheimer’s & Dementia: The Journal of the Alzheimer’s Association, demonstrates that elevated levels of placental growth factor…

Glioblastoma, the most aggressive form of brain cancer, has found a way to exploit one of the body’s most fundamental processes: circadian rhythms. New research from Washington University in St. Louis shows that glioblastoma tumors sync their internal clocks with the host’s daily cycles to drive growth, particularly in response…

Non-invasive imaging tests currently used at the bedside to monitor tissue conditions could help in the early detection of sepsis, preclinical research indicates. The optical spectroscopy technique, reported in The FASEB Journal, could one day be used to initiate sepsis treatment for patients in intensive care before their brains and…

A long-term study by researchers at the Imperial College London and Cardiff University suggests that men with cardiovascular disease (CVD) risk factors, including obesity, face cognitive decline as early as a decade before similarly affected women. The research, which analyzed data from 34,425 UK Biobank participants, found that men begin…