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Biomarker of Early-Stage Alzheimer’s Disease Discovered in Urine
A new study be researchers at Shanghai Jiao Tong University reveals formic acid may be used as a sensitive urinary biomarker that can reveal early-stage Alzheimer’s disease (AD).
Tau Biomarker in Alzheimer’s Disease May Aid Earlier Diagnosis
A newly identified biomarker could help treating physicians diagnose AD at an earlier stage than is now possible, as a patient transitions to mild cognitive impairment (MCI).
New Model Demonstrates How Defects in RNA Splicing Contribute to Alzheimer’s Disease
Researchers at St. Jude Children's Research Hospital in Memphis, TN have developed a new model for Alzheimer's disease demonstrating how defects in the RNA splicing machinery of the cell contribute to the condition.
Alzheimer’s Drug Could Be Winner for Biogen and Eisai
Lecanemab has achieved good results at Phase III for treatment of cognitive impairment in early Alzheimer's disease.
Hospital-Treated Infections Linked with Later Alzheimer’s and Parkinson’s
Contracting infections that need either in- or out-patient hospital treatment are linked with later Alzheimer’s or Parkinson’s disease at a relatively young age, Swedish research suggests.
Alzheimer’s Research: Molecular Changes in Brain Linked to APOE4
Investigators at the Keck School of Medicine of USC have published research showing that the APOE4 gene produces molecular changes in the brain’s blood vessels, which are then followed by changes in the synapses between brain cells.
Study Reveals How Microglia Contribute to Alzheimer’s Disease
Researchers from MIT have identified a mechanism which causes a type of cells in the central nervous system called microglia that express the APOE4 gene to be one of the strongest genetic risk factors for Alzheimer's disease.
Small Blood Vessel Disease in the Brain Linked to Worse Cognition in Alzheimer’s
Researchers discover a link between vascular dysfunction in the brain and worse cognitive function in individuals with Alzheimer's.
High Levels of Blood Enzyme May Point to Alzheimer’s Disease
University of California, San Diego scientists demonstrate how elevated levels of an enzyme called phosphoglycerate dehydrogenase in the blood of older adults may be an early warning sign of Alzheimer’s disease.
A Matter of Timing: Rudy Tanzi on Alzheimer’s Disease
In this interview Tanzi discusses his recent whole-genome sequencing studies and where the people have gone wrongin trying to address this condition.