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New evidence shows mutations in p53 contribute to the development of atherosclerotic cardiovascular disease.
Newly identified markers of atherosclerotic coronary artery disease (ASCAD) were pinpointed in a study using digital twins by G3 Therapeutics and Aitia.
Scientists have uncovered a link between mitochondria, inflammation, and two genes that normally help regulate blood cell growth—DNMT3A and TET2— that, when mutated, are associated with an increased risk of atherosclerosis.
Blocking PERK in smooth muscle cells blocks and decreases buildup of atherosclerotic plaque in mouse models, according to a new study from researchers at UTHealth Houston.
Researchers discovered that the gene—called SVEP1—makes a protein that drives the development of plaque in the arteries. In mice, animals missing one copy of SVEP1 had less plaque in the arteries than mice with both copies.
Researchers have discovered why a gene variant that is linked with facial flushing after drinking alcohol may increase the risk of coronary artery disease.
New insights from Canadian researchers help explain how the PCSK9 protein degrades low-density lipoprotein (LDL) and its role in atherosclerosis and cancer.
A digital marker for coronary artery disease has been developed by Mount Sinai researchers based on machine learning and clinical data from electronic health records.
Bromocriptine has the potential to slow down the development of cardiovascular abnormalities and disease in young people with type 1 diabetes.
Researchers successfully lower cholesterol levels in patients with cardiovascular disease using investigational drug Olpasiran.