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Transparent blue image of human heart with monitored beat to show that electrocardiogram results can predict diabetes

Mutated p53’s Role in Atherosclerosis Reinforced

New evidence shows mutations in p53 contribute to the development of atherosclerotic cardiovascular disease.
Atrial fibrillation and normal or abnormal heart rate rythm concept as a cardiac disorder as a human organ with healthy and unhealthy ecg monitoring in a 3D illustration style to illustrate sudden cardiac death

New Biomarkers for Atherosclerosis Found Using Digital Twins

Newly identified markers of atherosclerotic coronary artery disease (ASCAD) were pinpointed in a study using digital twins by G3 Therapeutics and Aitia.
Illustration of red blood cells moving through clogged Artery to indicate atherosclerosis and need for statin use

Findings Suggest Mitochondrial DNA Could be Atherosclerosis Drug Target

Scientists have uncovered a link between mitochondria, inflammation, and two genes that normally help regulate blood cell growth—DNMT3A and TET2— that, when mutated, are associated with an increased risk of atherosclerosis.
Illustration of red blood cells moving through clogged Artery to indicate atherosclerosis and need for statin use

Preventing Atherosclerosis by Inhibiting PERK

Blocking PERK in smooth muscle cells blocks and decreases buildup of atherosclerotic plaque in mouse models, according to a new study from researchers at UTHealth Houston.
Coronary artery disease (CAD)

Gene That Promotes Atherosclerosis Found

Researchers discovered that the gene—called SVEP1—makes a protein that drives the development of plaque in the arteries. In mice, animals missing one copy of SVEP1 had less plaque in the arteries than mice with both copies.
Blood vessel with platelets, white blood cells and red blood cells.

Facial Flushing Variant Linked with Blood Vessel Inflammation

Researchers have discovered why a gene variant that is linked with facial flushing after drinking alcohol may increase the risk of coronary artery disease.
Illustration of red blood cells moving through clogged Artery to indicate atherosclerosis and need for statin use

New Details Highlight PCSK9’s Role in Cardiovascular Disease and Cancer

New insights from Canadian researchers help explain how the PCSK9 protein degrades low-density lipoprotein (LDL) and its role in atherosclerosis and cancer.
Image illustrating man with cardiovascular disease

AI Generates In-Silico Marker That Predicts Heart Disease Risk

A digital marker for coronary artery disease has been developed by Mount Sinai researchers based on machine learning and clinical data from electronic health records.
Doctor Measuring Blood Pressure Of A Young Patient with type 1 diabetes to assess benefits of bromocriptine

Parkinson’s Medication Could Reduce Heart Disease in Type 1 Diabetes Population

Bromocriptine has the potential to slow down the development of cardiovascular abnormalities and disease in young people with type 1 diabetes.
Image illustrating man with cardiovascular disease

New siRNA Therapy Significantly Reduces Cholesterol Levels in Patients with Cardiovascular Disease

Researchers successfully lower cholesterol levels in patients with cardiovascular disease using investigational drug Olpasiran.

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