A recent study from Johns Hopkins Medicine reveals that commonly used arm methods of positioning a patient’s arm during blood pressure screenings can lead to significant overestimations of blood pressure readings, potentially resulting in misdiagnoses of hypertension. The research, published today in JAMA Internal Medicine, evaluated three arm positions commonly…

Good cardiovascular health in early pregnancy was linked to lower risk of hypertension even in women at genetic risk of the condition, according to preliminary research presented at the American Heart Association’s Hypertension Scientific Sessions 2024, September 5–8.  In a study of over 5,000 pregnant women, they found that, compared…

Merk announced today that its first-in-class drug, sotatercept-csrk (Winrevair), for the treatment of pulmonary arterial hypertension (PAH) has been approved by the U.S Food and Drug Administration (FDA). The drug has shown that it increases exercise capacity and reduces the risk of clinically worsening events. Sotatercept is the first FDA-approved…

Innovent Biologics and SanegeneBio have entered into a collaboration and co-development agreement for SGB-3908, an siRNA drug candidate targeting angiotensinogen (AGT) for the treatment of hypertension. Under the terms of the deal, Innovent will gain an exclusive option to license future development, manufacturing, and commercialization rights of SGB-3908. SGB-3908 is…

Roche will partner with Alnylam to develop the U.S. biotech’s RNA interference (i) candidate therapy zilebesiran for treatment of hypertension in a deal worth more than $310M. Zilebesiran is an RNAi therapy designed to reduce blood pressure by inhibiting hepatic angiotensinogen synthesis. It is long acting and currently being tested…

Treatment of apparent resistant hypertension (aRH) varies considerably, a new study finds. This form of high blood pressure requires more medication and medical management. These investigators learned that patients with well-managed aRH were more likely to be receiving a mineralocorticoid receptor antagonist, or MRA as part of their regimen. Such…

A new study from South Korea demonstrates how the gut microbiome can affect risk of hypertension. The team compared four major types of gut bacteria and found that Bacteroides2 had the strongest association with hypertension. The work was done by a research team at Kangbuk Samsung Hospital in collaboration with…

A simple test can detect genetic variants associated with hypertension and create individualized treatments that can improve blood pressure control. The fluorescent assay uses conjugated polymers and can detect two single nucleotide polymorphisms (SNPs) associated with hypertension in a single reaction. Personalized therapeutic schedules based on the test results dramatically…

A novel blood test based on cell-free DNA can evaluate severity of pulmonary arterial hypertension (PAH) and predict survivability. In early clinical studies, researchers at the National Institutes of Health showed the test significantly improves upon conventional tests, some of which are invasive. With further study, this first-of-its-kind blood test…

People with hypertension have more than double the risk of hospitalization related to Omicron infection, even if they are fully vaccinated and boosted, according to a new study led by investigators in the Smidt Heart Institute at Cedars-Sinai. Their findings appear this week in Hypertension. “The take-home message is that avoiding…

A non-invasive method developed by scientists at the University of Michigan allows patients to be scanned for an adrenal adenoma in a safer way, producing better quality images. Hypertension, or excessively high blood pressure, is a widespread problem and can lead to significant cardiovascular problems and events if left untreated.…

People with benign adrenal tumors are at higher risk for type 2 diabetes and high blood pressure than previously understood, according to new research from the University of Birmingham in the U.K. The study, published in the Annals of Internal Medicine, revealed that more of these tumors secrete abnormal levels…

A combination of computational and experimental research led by the University of Pittsburgh has discovered specific cancer drug candidates that show promise for treating the respiratory condition pulmonary hypertension. The researchers used an algorithm to find what are known as differential dependency networks (DDNs) of genes linked to cancer drug…

A new study led by researchers at the National Institutes of Health (NIH) adds more weight to previous findings implicating variants of the gene ARMC5 in the increased risk of hypertension in blacks. Researchers identified 17 variants in the gene that were associated with high blood pressure in individuals of…

Owlstone Medical, has announced a strategic collaboration with Switzerland-based Actelion Pharmaceuticals Ltd, leader in pulmonary arterial hypertension (PAH), to discover and validate a breath-based test to help facilitate the early diagnosis of pulmonary hypertension (PH) and its subtypes. Terms of the deal were not disclosed but the entire program will…