The trillions of microbes in the human gut play crucial roles in the development and progression of a range of autoimmune diseases, from inflammatory bowel disease to kidney disease and beyond. [CHRISTOPH BURGSTEDT/SCIENCE PHOTO LIBRARY/Getty Images]  As many as one in 10 people in the U.K.…

In a new study in mice, researchers from the University of California, Irvine (UCI), demonstrated how disruption of the circadian rhythm may accelerate the progression of colorectal cancer (CRC) by affecting the gut microbiome and intestinal barrier function. The new study offers new avenues for prevention and treatment strategies. The…

A new study will test microbiome biotech BiomeSense’s at-home gut microbiome monitoring technology in a collaboration with probiotic developer Pendulum Therapeutics. The study is small, but BiomeSense’s GutLab technology will allow regular gut microbiome monitoring in the participants’ homes, something that could allow a precision medicine approach to microbiome monitoring…

REGISTER NOW Panelists: Jason Bush, PhDChief Scientific OfficerSolnul®, (MSP Starch Products Inc.) Ken Chalcraft, PhDSenior Scientist-MetabolomicsDNA Genotek™ Heloise Breton, PhDSenior Product Manager-Microbiome & MetabolomicsDNA Genotek™(Moderator) Broadcast Date: September 25, 2024Time: 8:00 am PT, 11:00 am ET, 17:00 CET The human gut contains a universe of microbes constantly interacting with each other and…

The link between the gut microbiome and autism spectrum disorder (ASD) is strongly supported and expanded on by a new metagenomics study, published in Nature Microbiology from a Chinese team. Their analysis includes not just bacteria native to the digestive tract, but also fungi, archaea, and viruses too. Their work…

Metastatic kidney cancer patients who took a proprietary live bacterial supplement showed signs that it could improve their outcomes in a Phase I trial of cabozantinib and nivolumab, according to researchers at City of Hope. The microbiome supplement, Clostridium butyricum MIYAIRI 588 (CBM588), produces butyric acid, which is critical for…

A study of more than 8,000 gut microbiome profiles sampled from people in eight different countries led by researchers based at Harvard University shows abnormal changes in 19 bacterial species are linked to increased risk of developing type 2 diabetes. Of the 19 gut bacteria species identified, five were linked…

Quantitative methods paired with strict confounder control uncover more accurate microbiome colorectal cancer biomarkers, according to new research. Multiple microbial taxa have been put forward as potential cancer-associated biomarkers in the past, but this new study uncovers obscured contributions that may have resulted in incorrect associations.  This study shows that,…

Researchers at the Francis Crick Institute, the National Cancer Institute (NCI) of the U.S. National Institutes of Health, and Aalborg University in Denmark have discovered that vitamin D can increase the amount of a certain type of gut bacteria, providing better immunity to cancer.  Vitamin D is essential for human…

Research led by the University of Chicago shows an artificial intelligence (AI) driven “digital twin” modeling the infant microbiome can predict neurodevelopmental problems later in infancy. Using data on very early gut microbiome composition from fecal samples from preterm babies the digital twin predicted later microbiome composition and associated neurodevelopmental…

Researchers from the Broad Institute of MIT and Harvard together with Massachusetts General Hospital investigators have identified specific species of bacteria in the gut that consume bacteria to help lower cholesterol and decrease the risk of heart disease. The research, published Tuesday in the journal Cell, adds to the list…

A study led by the Navarra Institute for Health Research in Spain shows that specific gut bacteria are predictive of obesity, but that the species involved differ between men and women. Paula Aranaz, a researcher at the Center for Nutrition Research at the University of Navarra, will present the research…

Molecular “smart tweezers” that can select specific bacteria from a microbiome have been developed by researchers at the Icahn School of Medicine at Mount Sinai. Their technique, mEnrich-seq, exploits the natural signals that bacterial DNA uses to differentiate from each other.  Using this approach, the researchers can distinguish specific bacteria…

A link has been shown between eating certain types of fat and variations in lab mice’s microbiomes. Given the rise of diet-related human illnesses and the utility of the mouse model for these and the microbiome, this study could pave the way to understanding how these two factors interact. The…

A study involving 381 children has linked cognitive function with the enrichment or depletion of certain species of gut microbes. The findings are among the first to directly investigate associations between early brain development and specific gut bacteria, say lead author Kevin Bonham, of the Department of Biological Sciences at…