Researchers at the University College London (UCL) have developed a new handheld scanner that generates highly detailed 3D photoacoustic images in just seconds, an advancement that could provide for earlier diagnosis of cancer, cardiovascular disease, and arthritis. The study, published today in Nature Biomedical Engineering, details the technology at the…

A small research study by investigators at the Biomedical Research Institute of Málaga and Nanomedicine Platform, Spain, has shown that inflammatory activity from rheumatoid arthritis (RA) can cause cognitive impairment including diminished visuospatial abilities, recall, abstract thinking, and the executive functions of working memory, concentration, and inhibition. Their findings are…

A molecule known as resolvin T4 (RvT4) could help treat patients with rheumatoid arthritis-associated atherosclerosis in the future, according to research led by Queen Mary University of London. Between one and two million people in the U.S. have the degenerative autoimmune joint condition rheumatoid arthritis. Like many autoimmune conditions, people…

A study led by researchers at the Copenhagen University Hospital suggests that individuals with thumb osteoarthritis who have surgery have different genetic variants than individuals who have non-surgical treatment. It is early days, but the results of the study suggest that treatment outcomes or prognosis of this common and debilitating…

Researchers from the Broad Institute of MIT and Harvard and Brigham and Women’s Hospital have made significant strides in understanding rheumatoid arthritis (RA) through new research that provides a cellular atlas of RA defining six subtypes of inflammation. The study, published in Nature, examined the cellular drivers of RA by…

Real world research led by the Kobe University Graduate School of Medicine in Japan shows that Janus kinase (JAK) inhibitors are effective, non-invasive treatments for rheumatoid arthritis with manageable side effects. In the U.S., around 1.3 million people have rheumatoid arthritis and have to live with the chronic autoimmune condition,…

A team of scientists led by KOO Sagang from the Seoul National University and the Center for Nanoparticle Research within the Institute for Basic Science Center (IBS), in collaboration with researchers from Korea Institute of Science and Technology (KIST) and the Seoul National University, developed a new solution for treating…

Research suggests that people with allergic asthma or eczema are at increased risk for osteoarthritis compared with those without allergies. Osteoarthritis is the most common type of arthritis, impacting approximately one in seven adults in the U.S. “Osteoarthritis is associated with considerable morbidity—it is one of the major contributors to…

Finnish researchers at the University of Jyväskylä and the Central Finland Health Care District have created an artificial intelligence (AI) tool that can detect early knee osteoarthritis with an accuracy that matched 87% of doctors’ diagnoses. The researchers noted that being able to diagnose osteoarthritis early can help prevent unnecessary…

A large study led by the University of Alabama at Birmingham found 10 new areas in the genome linked to osteoarthritis, as well as potential drug candidates that could be repurposed to treat osteoarthritis based on the molecular targets they are designed to interact with. Osteoarthritis is a common, degenerative…

Rituximab, a monoclonal antibody therapy approved for treating rheumatoid arthritis and other autoimmune conditions, could be an effective first-line treatment for the autoimmune muscle condition myasthenia gravis according to a recent clinical study. In the trial, researchers from the Karolinska Institute in Sweden tested rituximab in a group of 47…

Research from Queen Mary University of London suggests that the reason patients with rheumatoid arthritis often have different responses to therapy could be due to their genetic profiles. Around 1.3 million adults are affected by rheumatoid arthritis in the U.S. There has been much progress in treating the autoimmune condition,…

Research led by Hokkaido University in Japan shows that remote inflammation, such as that seen in rheumatoid arthritis, spreads by neuron crosstalk regulated by adenosine triphosphate (ATP), according to findings from a mouse model. Their study published in the Journal of Experimental Medicine, may lead to new therapies for inflammatory…

Studies in mouse models conducted by researchers at the Washington University School of Medicine, indicated that an investigational anti-inflammatory drug, ATI-450, may also reduce some of the damaging side effects of the chemotherapy cocktail FOLFIRINOX (a combination of folinic acid, 5-fluorouracil, irinotecan and oxaliplatin), which is commonly used to treat…

Researchers at Washington University School of Medicine in St. Louis have genetically engineered cells that, when implanted in mice, deliver a biologic drug in response to inflammation. These cells reduced inflammation and prevented bone erosion in a mouse model of rheumatoid arthritis. The research team aims to develop therapies for…