Researchers from Mass General Brigham healthcare system have shown that one third of ChatGTP responses to questions about breast, prostate, and lung cancer treatment include recommendations that are at least partially nonconcordant with National Comprehensive Cancer Network (NCCN) guidelines. “Our results showed that the model is good at speaking fluently…

Just after 8:30 ET on Tuesday night a Commercial Resupply Services mission to the International Space Station (ISS) launched carrying 20 payloads of a diverse set of research projects to determine the benefits of working in microgravity. One of the projects, designed by Mayo Clinic and ClinImmune scientists in collaboration…

New data from researchers at VCU Massey Cancer Center shows that kidney cancer drugs that block blood vessel growth as a part of treatment significantly elevate the risk of heart problems in younger patients. The study, published today in the Journal of the National Comprehensive Cancer Network, assessed the incidence…

Eating a more substantial meal led to significantly higher blood concentrations of drug in patients taking an often-prescribed treatment for lung cancer. Alectinib (Genentech’s Alecensa) is a small molecule kinase inhibitor used to treat ALK positive, metastatic, non-small cell lung cancer. Taking a dose of alectinib with a small, low-fat…

Chimeric antigen receptor T cell therapy, commonly referred to as CAR T therapy, is an intervention that uses a patient’s own cells to fight their cancer. The therapy first received US Food and Drug Administration (FDA) approval in 2017. For some patients, this meant long term remission and even cures…

Researchers at Baylor College of Medicine and collaborators have developed and validated a multiparameter molecular classifier test that allows scientists to predict which HER2-positive breast cancer patients could be spared from chemotherapy by receiving anti-HER2 treatment only. About one in every five breast cancer patients is HER2-positive—meaning that the cancer…

Researchers at Harvard Medical School and National Cheng Kung University in Taiwan have developed a new artificial intelligence (AI) tool that examines tumor sample images to provide doctors with prognoses and guidance on the most appropriate treatments for colorectal cancer. According to the team, the tool can discern how aggressive…

As he devises a tiny plasmonic nanopore system to capture even rare antigens and their ligands from tumors, George Alexandrakis is toiling at the vanguard of cancer research. The University of Texas at Arlington bioengineering professor is developing a way of using even very small samples of tissue or blood…

Researchers at Northwestern University have developed a fast and non-invasive method to isolate tumor-reactive lymphocytes from peripheral blood instead of tumor tissue, potentially improving tumor-infiltrating lymphocyte therapy for cancers that are difficult to reach. Tumor-infiltrating lymphocyte (TIL) therapy is a type of immunotherapy where naturally occurring T cells that have…

It’s clear Black women face a much higher risk from breast cancer, in part because of lack of access to guidelines-based care. But what can doctors do about this state of affairs? The American College of Surgeons (ACS) has released a review that outlines some action points for surgeons. The…

A new study, led by investigators at Sylvester Comprehensive Cancer Center at the University of Miami Miller School of Medicine, has demonstrated for the first time the method by which immature neutrophils, a type of white blood cell are controlled by pancreatic cancers to drive both immunosuppression and treatment resistance.…

Researchers at University of Texas at Arlington are developing a tiny nanopore system to trap antigens so doctors can order highly personalized cancer therapies. The team is developing a method to use even very small samples to find peptide-presenting major histocompatility complex (MHC ) receptors and determine which T-cell receptor-like…

Researchers at Washington University (WashU) School of Medicine report they have identified a previously unknown signaling pathway in cells that protects their DNA while it is being copied—a discovery that suggests this pathway could be targeted for treating cancer by interfering with the disease’s ability to duplicate its genome. The…

A mouse study published in Nature Cell Biology by researchers at the Australian National University (ANU) and the Peter MacCallum Cancer Centre have discovered that a protein called Menin contributes to abnormal deactivation of specific genes in cancer cells. The team surmises that targeting the Menin protein, could reactivate these…

Researchers at the University of Waterloo in Canada have developed an AI-guided computational tool that can predict how a brain tumor will grow and spread based on magnetic resonance imaging (MRI) data. This model could help physicians to personalize treatments to brain cancer patients. Glioblastoma multiforme (GBM) is one of…