Researchers at the University of Alabama at Birmingham have described an underlying mechanism that reprograms the hearts of patients with ischemic cardiomyopathy, a process that differs from patients with other forms of heart failure, collectively known as dilated (non-ischemic) cardiomyopathies. This points the way toward future personalized care for ischemic…

Women who undergo open heart surgery are less likely to experience abnormal heart rhythm, known as atrial fibrillation, after surgery than men but those who do develop this complication are at greater risk for early death than their male counterparts. The study, published in JAMA Network Open and led by…

Researchers at the Fujita Health University in Japan report that adding a measure of how well kidneys are filtering blood called estimated glomerular filtration rate (eGFR) to an existing risk measure can more accurately predict sudden cardiac death (SCD) in patients with congestive heart failure. This new measure of risk,…

Researchers at University of California San Diego (UCSD) School of Medicine, along with colleagues at Rady Children's Institute for Genomic Medicine have conducted novel whole genome sequencing of a family in which two of four children were affected by Kawasaki disease (KD)—the most common acquired heart disease in children. The…

Results from a large study carried out in Michigan show 12 percent of hospitalized patients were misdiagnosed with community-acquired pneumonia and given full courses of antibiotics. Patients at highest risk for misdiagnosis were older, and more likely to have dementia or some other form of altered mental state on admission…

Researchers have found that the eye can provide a window into many different diseases, with thinner retinal layers having a genetic basis and an association with ocular and cardiometabolic diseases as well as neuropsychiatric conditions. The findings suggest that markers for systemic and ocular health could be developed from optical…

Researchers at the Mayo Clinic have discovered a connection between sleep apnea and brain biomarkers that have been linked to an increased risk of stroke, Alzheimer’s disease, and cognitive decline. As many as 18 million Americans suffer from a lack of deep sleep caused by interruptions in their breathing pattern…

Chemotherapeutic agents are widely known to carry an increased risk of heart failure and other forms of cardiovascular damage. A new study from the University of Toronto finds that Black patients or patients of African ancestry are at particular risk, with 71% higher odds of experiencing cardiotoxicity compared to White…

Polygenic risk score technology company Allelica announced that it will work with SP BioMED to conduct a study of breast cancer polygenic risk scores (PRS) using data of known breast cancer cases found in Taiwanese biobanks. The goal of the study is to determine the best technology to leverage for…

Two studies have revealed how artificial intelligence can accurately predict kidney complications in hospital patients, helping clinicians to instigate timely treatment or preventive care. The findings were presented at Kidney Week 2022, the meeting of the American Society of Nephrology currently being held in Orlando, Florida. In the first study,…

Rudolph E. Tanzi For the better part of four decades, Rudy Tanzi, PhD. has been one of the most prominent and influential researchers in the field of Alzheimer’s disease (AD) and other neurodegenerative disorders. Tanzi is a founder and/or advisor to multiple biotech companies, co-director of…

A new, updated risk score can help predict contrast-associated acute kidney injury (CA-AKI) among patients undergoing percutaneous coronary intervention (PCI), Mount Sinai researchers report.  According to their study, the tool can enhance management of patients at high risk of CA-AKI before, during, and after PCI, and improve prognosis following the…

A new report shows women are still underrepresented in clinical trials despite guidelines and laws requiring better representation set down 30 years ago. The findings come from the American College of Cardiology Cardiovascular Disease in Women Committee and are published in the Journal of the American College of Cardiology. They…

Once ovarian cancer cells slough off from their site of origin, they tend to find a new home in tissues with high fat content. Now, researchers have shown that those ovarian cancer cells use fats as an energy source. At the heart of the transition to fatty acid metabolism is…

Researchers from Imperial College London and the University of California San Diego School of Medicine say they have developed a blood test that can accurately identify Kawasaki disease (KD), an acquired childhood heart disease that can result in heart attacks, congestive heart failure, and death. The research published in JAMA…