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Published on January 16, 2024
Researchers from the UCLA Health Jonsson Comprehensive Cancer Center have published new research in the journal JAMA Oncology demonstrating that chemotherapy plus high doses of radiation are a safe and effective treatment for people with locally advanced non-small cell lung cancer (NSCLC) that is not suitable for surgery. The Jonsson…
Published on May 3, 2023
Originally Aired: May 18, 2023Time: 8:00 am PT, 11:00 am ET, 17:00 CET VIEW NOW SHORTLY To be implemented in the clinic, tests must be validated and approved through a regulatory process. Coverage and procedures for mutation types vary among the many available tests. There are various methods for EGFR mutation detection,…
Published on April 27, 2022
Cancer genetic testing company NeoGenomics and Eli Lilly and Company, through its Loxo Oncology unit, have entered into a sponsored partnership program that will see Lilly provide molecular testing for eligible patients with metastatic non-small cell lung cancer (NSCLC). The Lilly Lung Cancer Sponsored Testing Program will employ the NeoTYPE…
Published on June 4, 2020
About 15 percent of lung cancers are classified as small cell lung cancer. Recent studies have indicated that four major subtypes of small cell lung cancer exist, yet approaches to tailor treatment of these subtypes have not yet become standard of care. Now, scientists outline new findings “MYC Drives Temporal…
Published on January 14, 2025
Real-world survival associated with anti-cancer therapies is often significantly lower than that reported in randomized controlled trials (RCTs). Now, a new study demonstrates that a first-of-its-kind, AI-based platform could help clinicians and patients assess whether and how much an individual patient may benefit from a particular therapy being tested in…
Published on January 7, 2025
Dana-Farber Cancer Institute has announced the launch of the Center for RAS Therapeutics, a multidisciplinary initiative aimed at accelerating scientific research, improving treatment strategies, and advancing clinical care for patients with RAS-driven cancers. The new center will foster collaboration between Dana-Farber scientists and clinicians with industry partners and academic centers…
Published on December 3, 2024
A Phase III trial of a wearable electric field treatment for advanced pancreatic cancer, developed by Swiss biotech Novocure, met its primary endpoint and significantly improved patient survival time. These results are important, as this kind of cancer is notoriously difficult to treat so even small improvements in patient outcomes…
Published on November 13, 2024
An investigational vaccine designed by researchers at the Washington University (WashU) School of Medicine to prevent tumor recurrence has shown promising results in a phase I trial among patients with triple-negative breast cancer (TNBC). The neoantigen DNA vaccine targets patient-specific cancer neoantigens—mutant proteins or amino acid sequences that arise from…
Published on November 13, 2024
A new study from Providence Health presents a strong case for integrating complete genomic testing into the early stages of cancer diagnosis, arguing that doing so can significantly improve patient outcomes. Published this week in JCO Oncology Practice, the study demonstrates that implementing genomic profiling as part of the initial…
Published on September 25, 2024
Researchers at the Francis Crick Institute, in collaboration with Revolution Medicines, have shown that a combination of treatments can improve the effectiveness of immunotherapy in lung cancer. The study, published today in Nature Communications, indicates that simultaneous targeting of tumors using multiple treatment modalities could improve treatment response, particularly in…
Published on September 18, 2024
In an advance for AI in drug discovery, SOPHiA GENETICS, in collaboration with AstraZeneca, recently presented data generated using multimodal machine learning models to identify subgroups of stage IV non-small cell lung cancer (NSCLC) patients who could most benefit from a specific treatment—the addition of tremelimumab to durvalumab and chemotherapy.…
Published on September 4, 2024
Originally Aired: September 19, 2024Time: 8:00 am PT, 11:00 am ET, 17:00 CET VIEW NOW Early diagnosis and swift treatment are critical to changing the lung cancer landscape. Aligned with this goal, blood-based testing is a valuable tool to support clinical decision-making from diagnosis through monitoring. In this webinar, Dr. Gary Pestano…
Published on August 26, 2024
A lung cancer patient at University College London Hospitals (UCLH) was the first to receive a novel mRNA-based vaccine designed to prime the immune system to fight cancer cells very specifically. The BioNTech immunotherapy (BNT116) is being studied in a worldwide lung cancer trial. The NIHR UCLH Clinical Research Facility…
Published on August 21, 2024
New research from the Brigham and Women’s Hospital investigators has provided new details on different levels of cardiac risks for patient who receive radiation therapy to treat non-small cell lung cancer (NSCLC). The study, published in JACC: CardioOncology, leveraged artificial intelligence (AI) to uncover how different radiation doses impact specific…
Published on August 16, 2024
AstraZeneca (AZ) announced Thursday that its supplemental Biologic License Application has been granted priority review by the U.S. Food and Drug Administration (FDA) for the treatment of limited-stage small cell lung cancer (LS-SCLC). The regulatory decision is based on results of the ADRIATIC Phase III clinical trial in patients with…