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Ovary cancer

OTC Medicine Purchase Data Can Signal Ovarian Cancer

Data on over-the-counter (OTC) medicine purchases could spot ovarian cancer earlier, according to new research from a team in the U.K.
Treating Cancer

3D Models May Lead to Therapeutic Targets for Metastatic Ovarian Cancer

Researchers from the University of Pittsburgh Swanson School of Engineering were awarded a grant to determine the biology behind cell interactions that cause ovarian cancer to metastasize.
Illustration of female reproductive system including uterus and ovaries to represent ovarian cancer

Extra Surveillance for Women at Risk of Ovarian Cancer Can Be Effective in Short...

Short-term surveillance can help improve outcomes and treatment costs before preventive surgery in women at high-risk for ovarian cancer.
Illustration of female reproductive system including uterus and ovaries to represent ovarian cancer

RNA-based Algorithm Successfully Predicts Ovarian Cancers in Pelvic Mass

Known as MAGIC (Malignancy Assessment using Gene Identification in Captured Cells), the algorithm achieved a sensitivity for detecting epithelial ovarian cancer of 95% and an accuracy of 83% for detecting the disease.
3d rendered ovarian cancer illustration.

Multifactorial Strategy Shows Promise For Lethal Ovarian Cancer

Scientists from the University of California (UC), San Diego, and their collaborators have demonstrated how key proteins act together to suppress antitumor activity in high-grade serous ovarian carcinoma (HGSOC) in a mouse model, revealing a new combinatorial strategy to treat this intractable malignancy.
3d rendered ovarian cancer illustration.

Ovarian Cancer Genetics Shapes Tumor and Immune Cell Communication

Researchers have uncovered how tumor cells interact with the immune system in ovarian cancer. Utilizing highly multiplex immunofluorescence and image analysis, they investigated how the genetic characteristics of ovarian cancer shape how tumor and immune cells communicate with each other.
Illustration of female reproductive system including uterus and ovaries to represent ovarian cancer

Researchers Create Organoids that Model BRCA-Positive Ovarian Cancer

The fallopian tube-based organoids may help predict which individuals with BRCA-1 mutations will develop ovarian cancer years or even decades in advance, and could be used to develop personalized therapies.
Illustration of female reproductive system including uterus and ovaries to represent ovarian cancer

Ovarian Cancer “Achilles’ Heel” Revealed by UT Southwestern Researchers

This study identified mono (ADP-ribose) and NMNAT-2 as potential biomarkers for ovarian cancers, which may allow clinicians to determine which ovarian cancer patients may respond well and which will not and points to the therapeutic potential of developing an inhibitor for PARP-16.
Illustration of female reproductive system including uterus and ovaries to represent ovarian cancer

Moffitt Researchers Find Clues Underlying Humoral Immunity in Ovarian Cancer

Researchers from the Moffitt Cancer Center have discovered potential reasons why humoral immunity, or antibody-based immunity, appears to be associated with better outcomes in some ovarian cancers, potentially opening a new line of therapeutic intervention.
Illustration of female reproductive system including uterus and ovaries to represent ovarian cancer

Population-Wide Hereditary Breast, Ovarian Cancer Screening in Younger Women is Cost-Effective

The research suggests that wide screening of younger women for HBOC should be considered both to prevent more cancers and to help more women at low risk of breast cancer to avoid unnecessary additional screening.  

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