A small research study by investigators at the Biomedical Research Institute of Málaga and Nanomedicine Platform, Spain, has shown that inflammatory activity from rheumatoid arthritis (RA) can cause cognitive impairment including diminished visuospatial abilities, recall, abstract thinking, and the executive functions of working memory, concentration, and inhibition. Their findings are…

A molecule known as resolvin T4 (RvT4) could help treat patients with rheumatoid arthritis-associated atherosclerosis in the future, according to research led by Queen Mary University of London. Between one and two million people in the U.S. have the degenerative autoimmune joint condition rheumatoid arthritis. Like many autoimmune conditions, people…

Researchers from the Broad Institute of MIT and Harvard and Brigham and Women’s Hospital have made significant strides in understanding rheumatoid arthritis (RA) through new research that provides a cellular atlas of RA defining six subtypes of inflammation. The study, published in Nature, examined the cellular drivers of RA by…

Real world research led by the Kobe University Graduate School of Medicine in Japan shows that Janus kinase (JAK) inhibitors are effective, non-invasive treatments for rheumatoid arthritis with manageable side effects. In the U.S., around 1.3 million people have rheumatoid arthritis and have to live with the chronic autoimmune condition,…

A team of scientists led by KOO Sagang from the Seoul National University and the Center for Nanoparticle Research within the Institute for Basic Science Center (IBS), in collaboration with researchers from Korea Institute of Science and Technology (KIST) and the Seoul National University, developed a new solution for treating…

Rituximab, a monoclonal antibody therapy approved for treating rheumatoid arthritis and other autoimmune conditions, could be an effective first-line treatment for the autoimmune muscle condition myasthenia gravis according to a recent clinical study. In the trial, researchers from the Karolinska Institute in Sweden tested rituximab in a group of 47…

Research from Queen Mary University of London suggests that the reason patients with rheumatoid arthritis often have different responses to therapy could be due to their genetic profiles. Around 1.3 million adults are affected by rheumatoid arthritis in the U.S. There has been much progress in treating the autoimmune condition,…

Research led by Hokkaido University in Japan shows that remote inflammation, such as that seen in rheumatoid arthritis, spreads by neuron crosstalk regulated by adenosine triphosphate (ATP), according to findings from a mouse model. Their study published in the Journal of Experimental Medicine, may lead to new therapies for inflammatory…

Studies in mouse models conducted by researchers at the Washington University School of Medicine, indicated that an investigational anti-inflammatory drug, ATI-450, may also reduce some of the damaging side effects of the chemotherapy cocktail FOLFIRINOX (a combination of folinic acid, 5-fluorouracil, irinotecan and oxaliplatin), which is commonly used to treat…

A team of European researchers have shown a connection between the variance in the microbial composition in the mouths of people with early rheumatoid arthritis (ERA) and those at risk of developing the disease, compared with healthy individuals who were not at risk. The findings come from a study published…

Researchers part of a public-private partnership have identified new targets for the treatment of autoimmune diseases, including lupus and rheumatoid arthritis. That’s according to a trio of new studies published in the 18 June 2019 issue of Nature Immunologythat provide new details about how tissue damage occurs in these diseases.…

Interaction between genes and environmental factors is widely believed to increase the risk for rheumatoid arthritis (RA), but until now scientists haven’t understood the nature of this interplay. Studies by researchers at the University of Michigan, Ann Arbor, have now uncovered a mechanism by which a particular variant of the…

A new technique to analyze the cellular and molecular profiles of synovial tissue and peripheral blood to help develop more effective treatments for rheumatoid arthritis (RA), was detailed by researchers from Brigham and Women's Hospital, speaking recently at the American College of Rheumatology/Association of Rheumatology Health Professionals annual conference in San…

A new study by a team of researchers from Yale University has identified the mechanism of a gene that raises the risk of developing severe rheumatoid arthritis (RA)—a finding that may pave the way for the development of precision RA treatments based on the genetic profile of each patient’s arthritis.…

With the emergence of a wide array of new therapies for the management of rheumatoid arthritis, not only has treatment improved markedly over the past two decades, it has also grown increasingly complex. With 10 approved biologic therapies in the United States comes a growing need for tools that can…