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Published on January 4, 2024
A rare type of T immune cell can help predict which patients may benefit most from cancer immunotherapies, a new study has found. The study was published in Nature Cancer and led by researchers from King’s College London, Guy’s and St Thomas’ Hospital Trust, and the Francis Crick Institute. “Checkpoint inhibition (CPI),…
Published on October 11, 2023
Non-melanoma skin cancer (NMSC) causes more deaths globally each year than melanoma, which is considered a more aggressive form of skin cancer, shows research presented this week at the European Academy of Dermatology and Venerology Congress 2023. The higher number of deaths can be attributed to the substantially higher incidence…
Published on October 8, 2020
Melanoma, the deadliest skin cancer, can come out of nowhere—or so it may seem. After all, just 30% of melanomas arise from preexisting moles. More often, melanomas emerge from “normal” melanocytes that have accumulated DNA damage over years of exposure to the sun’s ultraviolet rays. Although this damage isn’t obvious…
Published on February 6, 2020
Researchers at the University of Arizona Cancer Center will use a $6.9 million gratn for the National Cancer Insitute (NCI) to look for effect ways to prevent skin cancer development and therapeutic strategies that can reduce the risk of non-melanoma skin cancer, such as squamous cell carcinoma of the skin.…
Published on March 7, 2016
A blood test may be able to sound early warning bells that patients with advanced melanoma skin cancer are relapsing, according to a study (“Application of Sequencing, Liquid Biopsies and Patient-Derived Xenografts for Personalized Medicine in Melanoma”) published in Cancer Discovery. Scientists from the Cancer Research UK Manchester Institute studied…
Published on October 12, 2023
A team of Moffitt Cancer Center researchers, in collaboration with NFlection Therapeutics and researchers at Stanford University, have identified a new drug, NFX-179, that can be applied to the skin and was shown to prevent the development of cutaneous squamous cell carcinoma in preclinical models. Cutaneous squamous cell carcinoma is…
Published on September 12, 2022
A striking 63.3% of patients with stage II–IV cutaneous squamous cell carcinoma (CSCC) saw their tumors nearly or completely disappear when treated with immunotherapy before surgery, according to an international, multicenter, Phase II clinical trial led by The University of Texas MD Anderson Cancer Center. The results were presented today at the European Society…
Published on February 22, 2021
High levels of the inflammatory immune biomarker interleukin (IL)-33 can trigger abnormal cell growth and division in skin and pancreatic cells, shows research from Massachusetts General Hospital. Chronic inflammation is known to be linked to a number of different cancers including skin, colon and pancreatic cancer. IL-33 is mostly known…
Published on October 31, 2024
Using spatial genomics technology, studies in preclinical animal models, and evaluation of tumor specimens from ovarian cancer (OvCa) patients, scientists at the Icahn School of Medicine at Mount Sinai discovered ovarian cancer tumors produce interleukin-4 (IL-4)—which is typically associated with asthma and the skin condition eczema—to produce a protective tumor…
Published on October 30, 2024
Despite advancements in cancer treatments, drug resistance continues to pose a significant challenge across a range of different therapeutic approaches. Now, new research from investigators at Kunming Medical University in China, published in Medcomm-Oncology, details the central role played by extracellular vesicles (EVs) in facilitating cancer drug resistance. The study…
Published on October 2, 2024
Australian researchers have shown that circulating antibodies against tumor antigens can be used as an accurate biomarker for the early detection of melanoma. The findings were presented by Cristina Vico-Alonso, MD, lead researcher from the Victorian Melanoma Service, in Melbourne, Australia, at the European Academy of Dermatology and Venereology Congress…
Published on September 30, 2024
Researchers at the University College London (UCL) have developed a new handheld scanner that generates highly detailed 3D photoacoustic images in just seconds, an advancement that could provide for earlier diagnosis of cancer, cardiovascular disease, and arthritis. The study, published today in Nature Biomedical Engineering, details the technology at the…
Published on August 7, 2024
A new study, published this week in the Annals of Internal Medicine, finds total expenditures for cancer screening in the U.S. topped $43 billion based on 2021 data. The research, led by Michael Halpern, MD, PhD, from the National Institutes of Health (NIH), used national health survey and resources data…
Published on July 31, 2024
Previous research has demonstrated that the lack of the gene MECP2 on microglial cells alters its functions, which might be implicated in Rett syndrome pathogenesis. Now, researchers at the University of California, San Diego (UCSD), have discovered an experimental cancer drug that targets faulty microglia which may improve cognitive function…
Published on July 9, 2024
A new AI image tool that selects high-risk women for magnetic resonance imaging (MRI) after negative mammography detects many missed breast cancers, interim findings from a clinical trial suggest. The AI-based system could help offset the extra costs of MRI that have prevented it from being included in national screening…