Diabetes and heart disease are two of the world’s leading causes of death, and the growth rate keeps increasing. Now, a team has estimated the contribution of sugar-sweetened drinks to Type 2 (TD2) diabetes and cardiovascular disease (CVD) burdens across 184 countries in 1990 and 2020, globally, regionally, and nationally.…

Data from an “unintended natural experiment from World War II” showed restricting sugar intake from conception through 1,000 days after birth was linked to a 35% lower risk of developing Type 2 diabetes and as much as 20% less risk of hypertension as adults. Low sugar intake by the mother…

The paradoxical surge of colorectal cancer (CRC) cases among younger adults is one of the biggest questions for oncology today. Now there is new evidence that an unexpected driver behind the mysterious rise of colon cancer cases in young adults is high blood-sugar levels.  This study found that young adults…

A recent study led by researchers at Cleveland Clinic has linked the sugar substitute xylitol to an increased risk of heart attack and stroke. Published in the European Heart Journal, the study found that higher levels of xylitol in the bloodstream are associated with a heightened risk of cardiovascular events,…

A pilot study of 148 people with high blood sugar conducted by researchers from Imperial College London (ICL) and testing company DnaNudge has shown that the use of personalized dietary advice based on genetic information, combined with face-to-face dietary coaching was, more effective at reducing blood sugar levels than standard…

A team of researchers from Moffitt Cancer Center have shown a novel approach to increase the numbers of tumor-infiltrating lymphocytes (TILs) and their antitumor activity. In research published in Nature Cancer, the investigators demonstrate, in mouse models, how L-fucose, a nontoxic dietary plant sugar that is enriched in red and brown…

Research led by Columbia University and carried out in mice suggests that eating a diet high in sugar and fat can negatively disrupt the microbiome and help contribute to onset of the metabolic syndrome, obesity, and type 2 diabetes. The study, published in Cell, showed that mice fed the equivalent…

Research shows that the oral diabetes medications metformin and glyburide are not as effective as insulin at reducing the number of babies born who are large for their gestational age. In addition, the University of Amsterdam-led study showed more cases of hypoglycemia in women treated with the oral medications versus…

Before reaching the market, new drugs are tested in people who voluntarily participate in clinical trials. However, for a new medicine to work in as many people as possible, these drugs should be tested in a patient population that is as diverse as possible. “I think about diversity through the…

The biggest and most comprehensive analysis of glucagon-like peptide-1 (GLP-1) receptor agonists on kidney and cardiovascular disease shows these drugs have significant benefits in people with and without diabetes. In both types of patients, the combined reduction in the risk of kidney failure, worsening kidney function, and death due to…

Researchers from the University of California (UC) Irvine have shown that variability in the gut microbiome can impact the pharmacokinetics of tamoxifen, which could explain why roughly 50% of women with breast cancer don’t respond to the treatment that reduces the risk of cancer recurrence. The finding published in the…

Novo Nordisk’s semaglutide (Wegovy) delivered impressive results against liver fibrosis and MASH (metabolic dysfunction-associated steatohepatitis) in a phase III trial, the company has reported. The trial showed a statistically significant and superior improvement in liver fibrosis with no worsening of steatohepatitis, as well as resolution of steatohepatitis with no worsening…

When compared to seven other anti-diabetic drugs, semaglutide may significantly lower the risk of Alzheimer’s disease in people with type 2 diabetes, according to new research from the Case Western Reserve School of Medicine. These results, which were based on data from a national health records database, were consistent across…

Some of the earliest observations of human health have proposed a connection between what is happening in the human gut and mental health—the now well-known gut–brain axis. However, researchers only began to make significant headway in these studies roughly 30 years ago. Today, research on the influence of the gut…

A recent study from researchers in South Korea contends that certain diabetes medications known as sodium-glucose cotransporter-2 (SGLT2) inhibitors may be linked to a reduced risk of developing dementia and Parkinson’s disease. The findings, published this week in the journal Neurology, are significant given the rising prevalence of these neurodegenerative…