We find ourselves in this issue focusing on the burgeoning field of proteogenomics and the advancement of single cell technologies being used to delve into the proteome more deeply. As the name infers, this combines both disciplines, the overlay of proteomics data combined with genomics data in an integrated fashion to help reveal new actionable insights at the molecular level. This links genotypes to phenotypes which of course is a central dogma of precision medicine. The transfer of information from DNA to RNA to proteins is one of the central tenets of molecular biology and is an area of intense scrutiny in precision medicine. Despite its apparent simplification to 3 iterative steps–the reality is rather more complex.
Nearly 33 years ago, we started out on a voyage to solve a huge genomic puzzle, 13 years later we had the first three billion lettered draft of the human genome. This was a laudable feat, deserving of the recognition the scientific and political community bestowed upon those that contributed to its completion. The promises of how this would unlock a raft of incurable genetic diseases unfortunately didn't materialize. Fast forward to this year, nearly two decades on, we have managed to fill in the gaps and create a complete genomic operating manual of human life. I hope this issue stimulates some thought around how far we’ve come and the ongoing path we need to follow. Educating as many as we can along the way will be one of our biggest challenges.
In this issue we hear from some of the individuals working in the infectious disease ecosystem who are committed to building the necessary foundations and implementing the requisite methodologies to deal with these viral invaders. Whether it is in the field of biosecurity, surveillance, data modelling, vaccine research, therapeutic and diagnostic development – the world needs to coalesce and develop a coordinated approach across all disciplines and across all borders.
In this issue we explore how the advent of digital pathology will not only improve efficiencies of scale, save time, reduce workloads, create more precise and accurate diagnoses, but will provide insights that will ultimately pave the way for a deeper pipeline of targeted
therapeutic candidates.
Read the April Inside Precision Magazine in its digital edition format. Get the latest news and information in precision medicine, molecular diagnostics, and more.
Read the February Inside Precision Magazine in its digital edition format. Get the latest news and information in precision medicine, molecular diagnostics, and more.
Read the November/December Clinical OMICs Magazine in its digital edition format. Get the latest news and information in precision medicine, molecular diagnostics, and more.
