Next-Generation Sequencing Test for Cutaneous Melanoma

New Test Predicts Melanoma Spread, Recurrence

U.K. researchers detail how early-stage melanomas at risk of spreading secrete a growth factor, TGFβ2, that causes downregulation of the proteins AMBRA1 and Loricrin—both of which are found in the skin overlaying the tumor.
Asian boy using inhaler containing medicine to stop coughing

NS2 Protein Instrumental in Long Term Respiratory Syncytial Virus Inflammation

NS2 protein identified as factor that prevents long-term inflammation from respiratory syncytial virus and possibly other respiratory viruses.
Big genomic data visualization

Sema4 to Acquire GeneDx for Approximately $623 Million

Central to the deal was GeneDx’s rare disease diagnosis and clinical exome sequencing capabilities along with data from more than 300,000 exomes and 2.1 million annotated patient phenotypes.
Male scientist working in Oxford Nanopore Technologies' genetic sequencing lab

Whole Human Genome Sequenced in Just Over Five Hours in New Record

New Guinness world record for human genome sequencing of less than 6 hours, set at Stanford University using Oxford Nanopore's sequencing technology, helps identify genetic disease in less than 8 hours.
Single-Cell RNA-Seq System

New Spatial Transcriptomic Tool Maps Cell Location and Function in Fine Detail

A tool that can pinpoint the location of detailed immune cell types in the human gut and lymph node, as well as map the fine-grained structure of the mouse brain has been developed by researchers based at the Wellcome Sanger Institute.
Genomenon said today it has partnered with Rhythm Pharmaceuticals to create a database of genetic mutations associated with obesity as documented in published studies. Rhythm plans to use the data to better understand rare genetic disorders of obesity. [Visual Mozart/Getty Images]

Genetic Insights into Pathways Behind Obesity Uncovered

A new study by researchers from the department of twin research and genetic epidemiology, King’s College London, and the NIHR BioResource, has revealed genetic pathways underlying obesity.
Senior male smoking cigarette on black background

Blood Test Improves Selection for Lung Cancer Screening in Long-Term Smokers

The four-marker protein panel (4MP) includes four proteins—the precursor form of surfactant protein B, cancer antigen 125, carcinoembryonic antigen, and cytokeratin-19 fragment—that have previously shown potential to identify people at risk of developing lung cancer.

Infection Diagnostics Company MeMed Raises $93M in Private Financing

MeMed’s core technology—it’s MeMed BV test run on the MeMed Key testing platform—is able to quickly distinguish whether a patient has a bacterial or a viral infection to allow physicians to either properly prescribe antibiotics, when needed, but also to avoid prescribing them if a patient is suffering from a viral infection.
Biotechnology, Scientist pipetting sample into a multi well plate.

Proteogenomics Consortium Launched by Seer, Discovery Sciences, SCIEX

According to the companies, the consortium will create an infrastructure capable of analyzing and cataloging one billion peptides each year, data which should lead to the identification of new protein variants and novel biomarkers, as targets for the development of potential new therapies.
Illustration of woman's head showing front part of brain lit up to symbolize problems in the prefrontal cortex

Early-Stage Research Uncovers Female Specific Biomarker for Depression

Through research done mostly in a mouse model, Canadian scientists have identified a biomarker, soluble E-selectin, that could be used to test whether women, but not men, have neurovascular signs of depression.