According to the companies, the consortium will create an infrastructure capable of analyzing and cataloging one billion peptides each year, data which should lead to the identification of new protein variants and novel biomarkers, as targets for the development of potential new therapies.
Researchers have developed a test that can not only indicate the presence of depression, but it can also indicate therapeutic response with a single biomarker called adenylyl cyclase.
Under the terms of the agreement, Iktos will apply its generative learning algorithms which seek to identify new molecular structures with the potential to address a novel target in Parkinson's disease.
The researchers have found a way to degrade components of SWI/SNF, a chromatin remodeling complex. These components are ATPases that provide the energy SWI/SNF needs to unwrap DNA and expose enhancer elements that crank up the expression of cancer-driving genes.
The researchers analyzed the cerebrospinal fluid of individuals with autism and epilepsy, and in mouse models. Previous studies have analyzed the cerebrospinal fluid from patients with Alzheimer’s and Parkinson’s diseases to help diagnose disease and measure response to treatment, but this study is the first to show the protein as a biomarker in autism.
This Inside Precision Medicine webinar, sponsored by ICON, will focus on the ability of digital technologies, including magnetic resonance imaging (MRI), magnetic resonance elastography (MRE), and whole slide imaging (WSI), to address some of these challenges.
Colorectal cancer patients may have more drug options if a systems approach to biomarker identification is used, suggests research from the Salk Institute for Biological Studies.
Research suggests prostate-specific membrane antigen positron emission tomography/computed tomography can detect low-volume, non-localized prostate cancer not seen with conventional imaging and improve prognosis prediction.
The first in-depth reference map of the uterus to collect both single cell and spatial transcriptomic data reveals new insights into the cellular make up of endometrial cancers and adds to the Human Cell Atlas.
One of the CEGS’s early projects will be led by Jaffrey to map the functional modifications that occur across the “transcriptome,” the complete set of all the mRNAs in a cell.