UltiMapper® I/O Immuno8™
Translational immuno-oncology research often requires the visualization of multiple cell phenotypes in FFPE tissue sections. Ultivue’s UltiMapper® I/O and U-VUE® kits allow for pre-optimized staining of up to 12 targets in a single tissue section using exchange technology with sequential imaging of targets across two or three imaging rounds. Final high-plex images require careful image alignment between scans to identify cell phenotypes in downstream analysis without artifacts from inappropriately overlapped cells, which can be achieved using Ultivue’s UltiStacker™ software.
Utility of the Immuno8™ panel for whole-slide, single staining step multiplexing assay coupled to same slide H&E analysis provides exceptional data quality and throughput, with sample-to-analysis workflow achieved in a single workday executed manually or through automation using instrumentation and software solutions currently found in most immunohistochemistry laboratories.