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Published on February 21, 2023
In a study including data from almost two million individuals, COVID-19 vaccination seemed to have a protective effect against heart attacks, strokes, and cardiovascular problems linked to infection with SARS-CoV-2. Research shows that even a mild case of COVID-19 can result in cardiovascular complications, often linked to abnormal blood clotting…
Published on February 17, 2023
Previous coronavirus infection lowers the risk of hospitalization or death by nearly 90 percent for at least 10 months compared with no prior infection, according to the most comprehensive analysis of studies to date. The protection conferred by past infection against reinfection with pre-omicron variants was very high and remained…
Published on February 10, 2023
William Haseltine It is becoming increasingly clear that we have misunderstood SARS-CoV-2, the virus that causes COVID-19. Many people, including some experts in the scientific community, deemed the pandemic over with the release of the mRNA vaccines. The belief—or perhaps it was hope in disguise—was that…
Published on January 4, 2023
Young adults and adolescents that suffered from rare cases of myocarditis following vaccination with a mRNA-based COVID-19 vaccine had increased levels of the viral protein spike in their bloodstream, found a recent study carried out by a team at Brigham and Women’s Hospital and Massachusetts General Hospital. However, it also…
Published on December 20, 2022
The COVID-19 pandemic is not over. It will not pass simply because we have grown tired of it. But it is equally misguided to think we are no better off now than we were during the early days of 2020. The past three years have yielded an immense amount of…
Published on October 18, 2022
A new study has produced a proof of principle for a new “universal” means of treating COVID-19. Using messenger RNA packaged in lipid nanoparticles, scientists showed in a mouse model that host cells can produce a “decoy” enzyme that binds to coronavirus spike proteins, meaning the virus shouldn’t be able…
Published on October 4, 2022
The risk of myocarditis from COVID-19 vaccination was higher in males and increased with the number of vaccinations and boosters that people received, according to a new study in Annals of Internal Medicine that was led by researchers at Kaiser Permanente Vaccine Study Center. There have been worldwide reports of…
Published on September 16, 2022
Hybrid immunity (vaccination plus infection) is the most robust and long-lasting protection against COVID-19, according to a new study of Catalonian patients. The researchers also found antibodies were no longer detectable almost a year after non-vaccinated people had COVID-19, particularly people older than 60 years and smokers. The researchers’ final…
Published on August 16, 2022
Every virus has its preferred niche — a particular host or demographic it is more inclined to infect and a particular set of strategies and tactics it uses to achieve this. A virus develops a niche over millions of years, all the while adapting and mutating in response to host…
Published on July 22, 2022
A new study has uncovered more details about memory B cell responses to SARS-CoV-2, the virus that causes COVID-19, after recovery from natural infection or post-vaccination. The study, coauthored by David Fear, from King’s College London, is published in Viral Immunology. Many research studies have found that serological SARS-CoV-2-specific IgG antibody…
Published on July 21, 2022
People with hypertension have more than double the risk of hospitalization related to Omicron infection, even if they are fully vaccinated and boosted, according to a new study led by investigators in the Smidt Heart Institute at Cedars-Sinai. Their findings appear this week in Hypertension. “The take-home message is that avoiding…
Published on April 21, 2022
Arcturus Therapeutics, a San Diego biotech with ‘self-amplifying’ RNA technology, announced its COVID-19 vaccine has reached its primary endpoint in a phase III trial this week. The trial included more than 16,000 people and took place in Vietnam with help from Vietnamese pharma company Vinbiocare. While the vaccine prevented the…
Published on April 20, 2022
German researchers have created a new vaccine against SARS-CoV-2—CoVac-1—that induces a T cell immune response in a high proportion of patients with leukemia and lymphoma. These patients are at high risk for severe COVID-19 because they are often receiving B cell depleting therapy which means that they cannot mount sufficient…
Published on March 16, 2022
New research among patients with cancer indicates differing immune responses to COVID-19 vaccination with an mRNA vaccine (Moderna’s mRNA-1273). The findings from the Moffitt Cancer Center also revealed variable antibody responses differing by cancer diagnosis and treatment. A paper summarizing their findings is published in JAMA Oncology. “The good news…
Published on January 26, 2022
A study by researchers at Mayo Clinic Cancer Center has found that patients with cancer who receive chemotherapy, and some targeted therapies including CDK4/6 inhibitors and therapies targeted at B cells, may mount an inadequate immune response to COVID-19 vaccination. The findings are published in Mayo Clinic Proceedings: Innovation, Quality & Outcomes. SARS-CoV-2…