76 Results
Sort By:
Published on June 6, 2019
The NIH plans to spend $42 million over five years to fund clinical trials designed to evaluate whether and how the management of diseases such as high blood pressure, depression and chronic pain can be improved through genomic medicine. The trials to be funded constitute the second phase of the…
Published on March 25, 2024
A team of investigators from The Australian National University (ANU) reporting today in Nature Communications say they have discovered a gene mutation that is responsible for causing psoriasis, the chronic inflammatory disease that results in red, scaly, itchy patches on the skin. The researchers showed that if two copies of…
Published on November 10, 2023
Sponsored by This IPM podcast unpacks some of the important work being done by Emma Johnson, PhD, assistant professor, department of psychiatry at Washington University School of Medicine. We discuss her mission to elucidate the genetic architecture of psychiatric disorders, particularly focusing on substance use and addictions. We hear…
Published on May 19, 2023
U.K.-based Closed Loop Medicine and Pharmanovia announced this week that they will partner to develop precision medicine combination therapies. The first product in development will combine a hypertension drug from Pharmanovia’s portfolio with software developed by Closed Loop to provide optimal personalized dosing. High blood pressure or hypertension is the…
Published on August 3, 2022
Eighteen new genetic risk factors for opioid use disorder (OUD) and related substance use disorders have been found though a large-scale genome-wide association study. Previously, there was only one gene linked so far to these conditions. The findings, published in Molecular Psychiatry, were made by a team of Yale scientists. “Our…
Published on June 15, 2022
Many biologists seek signals of gene expression and study the structure of tissues. Sequencing RNA (RNA-seq) reveals gene expression, and techniques evolved into single-cell RNA-seq (scRNA-seq), which uncovers the gene expression in just one cell. For spatial information about organisms, scientists use microscopy. To put together these two methods, scientists…
Published on February 16, 2022
Larisa Cavallari,University of FloridaCollege of Pharmacy When University of Florida (UF) Health started recommending genotyping to guide clopidogrel prescribing about ten years ago it was a “life or death issue,” explains Larisa Cavallari, professor of Pharmacotherapy and Translational Research at UF. The drug is administered after…
Published on November 5, 2021
Under a new, expanded agreement, rare disease diagnostic company Centogene will provide genetic testing and clinical trial support for three global, pivotal trials of Agios Pharmaceuticals’ PK activator in thalassemia and sickle cell disease. Agios is a leader in the field of cellular metabolism for developing treatments for genetically defined…
Published on June 18, 2020
Women with endometriosis, a painful condition that causes womb-like tissue to grow outside the uterus, have epigenetic changes in the DNA of their reproductive cells that may predispose them to developing the condition. “The findings raise the possibility that differences in methylation patterns could one day be used to diagnose…
Published on March 24, 2020
Data-based medicine might sound like a better way to treat patients. The advances in collecting information, especially sequencing genes, promise to push physicians closer to improved patient care. Even more, the combination of information on a patient’s genes (genotype) and traits (phenotype) could be combined to make smarter decisions on…
Published on February 10, 2020
The results of research headed by scientists at Japan’s Fujita Health University suggest that a metabolite in the kynurenine (KYN) pathway could represent a clinical biomarker for identifying individuals with depression-like symptoms who are at risk of developing major depressive disorder. The KYN pathway is the main pathway involved in…
Published on December 16, 2019
Genomind said today it will offer its Genomind Professional PGx Express mental health genetic tests at the pharmacies of all ACME Markets Inc. supermarkets in Pennsylvania, expanding a year-and-a-half-old partnership with ACME’s parent company Albertsons. The expanded collaboration—whose value was not disclosed—will bring Genomind’s test to 59 locations nationwide from…
Published on August 5, 2019
Genomind said today it will launch an enhanced version of its mental health genetic test that will feature a new, more focused report and set of services, all designed to help clinicians better understand a patient’s genetic profile and its implications for mental health treatment. Genomind Professional PGx Express, set…
Published on June 24, 2019
Diffuse, widespread, and chronic pain, such as that caused by fibromyalgia, is often frustratingly difficult to understand. Concentrating on the gut, however, may yield new insights. It may even simplify the diagnosis of notoriously hard-to-pin-down conditions. This would be welcome news to fibromyalgia patients, who can endure long waits—four to…
Published on November 10, 2017
Assurex Health, a wholly-owned subsidiary of Myriad Genetics, said today its GeneSight genetic test will be studied in veterans diagnosed with major depressive disorder (MDD) through a partnership with the U.S. Department of Veterans Affairs. GeneSight will be evaluated in the PRIME Care (PRecision Medicine In MEntal Health Care) study,…