Genomind said today it will offer its Genomind Professional PGx Express mental health genetic tests at the pharmacies of all ACME Markets Inc. supermarkets in Pennsylvania, expanding a year-and-a-half-old partnership with ACME’s parent company Albertsons. The expanded collaboration—whose value was not disclosed—will bring Genomind’s test to 59 locations nationwide from…

In the largest study of its kind, researchers at Massachusetts general Hospital have learned that eight psychiatric disorders have common genetic links. Studying GWAS data from healthy controls and individuals with at least one psychiatric disorder, they identified 109 gene variants associated with an increased risk for more than one…

People with autism or ADHD share certain rare mutations, according to researchers from iPSYCH in Denmark, the Broad Institute and Harvard. One of the most commonly shared types of mutations were those affecting the microtubule-associated protein 1A gene (MAP1A), which is involved in the formation of nerve cells. According to…

Mount Sinai Health System said today its researchers will be able to explore more complex scientific questions more quickly once the New York City health system builds its second “Big Omics Data Engine” (BODE 2) supercomputer, to be funded through a $2 million grant awarded by the U.S. Department of…

Eric Dishman, Director of the NIH’s All of Us Research Program The NIH’s All of Us Research Program has chosen the HudsonAlpha Institute for Biotechnology to assess the use of DNA sequencing technologies for diagnosis and treatment of common and rare diseases, under a $7 million…

The results of a study headed by researchers at the University of Chicago suggest that there may be a significant link between exposure to environmental pollution and the prevalence of neuropsychiatric disorders. Analyses of large population data sets from the United States and Denmark linked poor air quality with increased…

Genomind said today it will launch an enhanced version of its mental health genetic test that will feature a new, more focused report and set of services, all designed to help clinicians better understand a patient’s genetic profile and its implications for mental health treatment. Genomind Professional PGx Express, set…

Researchers studying nearly 147,000 veterans diagnosed with PTSD found that the disorder’s most characteristic symptom—re-experiencing—is associated with eight separate regions of the genome in whites. It is one of the largest genome-wide association studies (GWAS) of its kind to date. “Post-traumatic stress disorder (PTSD) is a major problem among military…

Scientists at Trinity College Dublin published a paper in JAMA that represented the largest ever study (“Lifetime Risk and Heritability of Amyotrophic Lateral Sclerosis”) involving 1,117 people diagnosed with motor neuron disease (MND) to address the question of “nature versus nurture” in the causes of MND, also known as Amyotrophic…

Treating psychosis by targeting a genetic mutation alleviates symptoms. That’s according to a new, proof-of-principle study that just may pave the way for precision medicine in psychiatry. The study, published in the July issue of Biological Psychiatry, is one of the first to treat psychosis based on genetics rather than…

The transfer of human microbiota to mice has successfully transplanted phenotypes of obesity, depression, Parkinson’s disease, schizophrenia, and multiple sclerosis. Now, we can add autism spectrum disorder (ASD) to the list. A new study suggests that the gut microbiome and its metabolites contribute to hallmark ASD behaviors and associated neuronal…

The New York Genome Center (NYGC) will receive a combined $125 million gift from the Simons Foundation and The Carson Family Charitable Trust, saying the money will help support the Center’s growth and research into autism, ALS, dementia and cancer. NYGC said the gift, to be awarded over five years,…

The pathophysiology of the brains of Alzheimer’s disease (AD) patients is widely studied. So too are global expression changes revealed by bulk transcriptomic analyses. Now, for the first time, researchers have performed a comprehensive analysis of genes expressed in individual brain cells of patients with AD using single-nucleus RNA-seq (snRNA-seq) profiles, identifying distinctive cellular…

The largest ever study of gene associations in bipolar disorder has been completed by Mount Sinai School of Medicine researchers and has identified 30 genome-wide significant loci, including 20 that are novel. More than 50,000 subjects in 14 countries and more than 200 collaborating institutions participated in this large-scale genome-wide…

A collaboration launched today by Illumina and the Lundbeck Foundation GeoGenetics Centre at the University of Copenhagen plans to generate and analyze one of the largest sets of ancient human and pathogen genome panels ever created—with the goal of underpinning new approaches to developing treatments for mental and neurological conditions.…