Multidimensional, computationally rich approaches represent the next wave of innovation, taking personalized medicine to the next level, while demanding more of practitioners, who in turn demand convenient, informative updates on the ever-changing state of clinical omics,” Clinical OMICs noted in introducing itself to readers with its first issue, dated April…

Children’s Hospital of Philadelphia has launched the Center for Computational and Genomic Medicine, a research center designed to marry computational biology and experimental biology Computational biologist Yi Xing, Ph.D., leads the center, which includes the approximately 20-member laboratory team that he relocated over the summer from the University of California,…

Partitioning is expensive, but barcoding is cheap—that’s the idea behind a new technique for single-cell analysis. By dispensing with fancy cell sorters, custom microfluidics, and microwells, and introducing budget-friendly combinatorial barcoding, this new technique promises to democratize single-cell transcriptomics. The new technique, which is called split pool ligation-based transcriptome sequencing…

Researchers at the Garvan Institute in Sydney, Australia, recently acknowledged what could be called a one-in-a-million milestone and then some. On December 14, Garvan investigators led by Martin A. Smith, Ph.D., head of genomic technologies in the Kinghorn Centre for Clinical Genomics, announced via Twitter that they had sequenced a…

Sponsor: OnRamp Bioinformatics The RosalindTM genomics analysis platform named in honor of pioneering researcher Rosalind Franklin, who made a major contribution to the discovery of the double-helix structure of DNA with her famous photograph 51 aims to sim­plify the practice of genomic data interpretation. Rosalind overcomes a number of the…

A new technique to analyze the cellular and molecular profiles of synovial tissue and peripheral blood to help develop more effective treatments for rheumatoid arthritis (RA), was detailed by researchers from Brigham and Women's Hospital, speaking recently at the American College of Rheumatology/Association of Rheumatology Health Professionals annual conference in San…

The potential of genomic sequencing technology to help in the fight against cancer was recognized at an early stage, with the first report of cancer genome sequencing in breast and colorectal tumors appearing in 2006, just five years after completion of the Human Genome Project. Since then, efforts such as…

The Melanoma Research Alliance (MRA) said today it has awarded more than $8.5 million in new funding, in 34 new research awards, to 28 institutions in six countries, all aimed at advancing treatment and understanding of the most serious type of skin cancer. The grants are intended to fund programs…

NantOmics, a molecular diagnostics developer and part of the NantWorks umbrella of nine companies founded by Patrick Soon-Shiong, M.D., has acquired Genos, a Complete Genomics spinout focusing on personal genetic discovery and research, for an undisclosed price. Genos offers whole-exome DNA sequencing through a $499 saliva kit that the company…

A new study from investigators at 10x Genomics and the Fred Hutchinson Cancer Research Center demonstrated the ability of a newly developed single-cell RNA-sequencing (scRNA-seq) system that can be used to dissect transcriptomic heterogeneity from patients with acute myeloid leukemia (AML). Findings from the new study were published online today…

Sponsor: Dolomite Bio The new Single-Cell RNA-Seq System has been developed for efficient, high-throughput, single cell transcriptomics. This compact, scalable system enables rapid, reproducible droplet encapsulation of individual cells, allowing up to 10,000 single cell libraries to be generated in one 15-minute run. The Single-Cell RNA-Seq System allows up to…

To highlight its new Twins Study—and to coincide with National Twins Day—NASA’s Human Research Program (HRP) is releasing a new video entitled “Omics: Advancing Personalized Medicine from Space to Earth.” This is the final video in a series of eight which explores space through you by using omics to look…

Though it may seem to be navigating by perceptibly unfixed stars, next-generation sequencing (NGS) is journeying ever more adventurously into the obscure, the rare, and the confoundingly heterogeneous domains within life’s molecular codescapes. NGS is already capable of producing billions of short reads, and it can do so quickly and…

Averages shout, and individuals whisper. That, in a nutshell, is the frustration of single-cell transcriptomics. Although innumerable cell types have unique gene-expression profiles, they are hard to discern. Great, thundering herds of cells typically give up their RNA to be sequenced all in one batch. It is possible to effectively…

Technological advances such as high-throughput sequencing are transforming medicine from symptom-based diagnosis and treatment to personalized medicine as scientists employ novel rapid genomic methodologies to gain a broader comprehension of disease and disease progression. As next-generation sequencing becomes more rapid, researchers are turning toward large-scale pan-omics, the collective use of…