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Published on April 23, 2024
A big challenge with the SARS-CoV-2 virus, which causes COVID, is that it regularly generates variants. Now, a new targeted RNA consensus sequencing method (tARC-seq) can accurately determine SARS-CoV-2 mutation frequency and types, both in cell culture and clinical samples, according to researchers at Baylor College of Medicine and collaborating…
Published on April 12, 2024
Researchers at Stanford Medicine say that immune cells in the lungs known as interstitial macrophages are critical in the development of severe—and potentially deadly—COVID. Their findings, published this week in the Journal of Experimental Medicine, showed that the these cells which are located deep in the lungs and normally protective,…
Published on March 20, 2024
SARS-CoV-2, the virus that causes COVID-19, can damage the heart in patients with ARDS (Acute Respiratory Distress Syndrome) without directly infecting heart tissue, a new study has found. These findings suggest it is systemic inflammation that causes this damage. “The research also suggests that suppressing the inflammation through treatments might…
Published on March 15, 2024
It is time to stop using terms such as “long COVID” an Australian research team says. Such phrases, they say, imply there is something unique about longer term symptoms associated with COVID. But long COVID, this team maintains, is just a typical post-viral syndrome, indistinguishable from what is seen with…
Published on March 13, 2024
The National Institutes of Health (NIH) announced Tuesday the launch of two Phase II clinical trials to evaluate the safety and effectiveness of three treatments for adults suffering from long COVID with autonomic nervous system dysfunction. The trials are a part of the NIH’s Researching COVID to Enhance Recovery (RECOVER)…
Published on March 8, 2024
T cell populations can change significantly after each COVID mRNA vaccine or booster, a new study from Japan demonstrates. The study, which included about 40 patients and used TCR sequencing, shows certain spike epitopes can become immunodominant. In addition, the team found intra-epitope shifts of vaccine-responding immune cell clonotypes. The…
Published on March 5, 2024
A large study led by Kyung Hee University in Seoul shows that infection with SARS-CoV-2 significantly increases the risk of developing autoimmune inflammatory rheumatic disease for up to a year after infection. The research, published in the Annals of Internal Medicine, shows that COVID-19 increased the risk for being diagnosed…
Published on March 4, 2024
Research led by the University of Cambridge shows that low iron levels and disrupted iron regulation in the body due to the viral infection may be contributing to long COVID symptoms. Although reports on exact numbers differ, it is thought that up to 30% of all people infected with SARS-CoV-2…
Published on February 22, 2024
Interferon gamma (IFN-γ) is a potential biomarker for Long COVID fatigue and this finding could be the basis for new therapies for the condition, a University of Cambridge-led study suggests. It’s known that SARS-CoV-2 triggers the production of the antiviral protein IFN-γ, which is associated with fatigue, muscle ache, and…
Published on February 21, 2024
A new study has shown that delays in diagnosis of melanoma in Europe due to COVID-19 lockdowns may have contributed to the loss of more than 100,000 life-years and costs that exceed £6 billion, mostly related to loss of productivity. The research, published last week in a new JAMA Network…
Published on February 12, 2024
A National Institutes of Health (NIH) study has found that 5.8 million children have experienced long COVID—symptoms of COVID-19 that have persisted long after the initial infection. The Nationwide research effort called the Researching COVID to Enhance Recovery (RECOVER) Initiative involved 10 pediatric hospital in the U.S., sought to provide…
Published on February 5, 2024
While researchers have already shown that insomnia was common in patients who have been hospitalized for COVID-19, new findings from a team of scientists in Vietnam found that insomnia was more likely in more than three-quarters of patients who had been diagnosed with a mild infection. The research, reported in…
Published on January 24, 2024
Babies of mothers infected by COVID-19 during pregnancy had three times the risk of respiratory distress compared with unexposed infants, even though the infants themselves were not infected with the virus, in a recent study. The risk of respiratory distress was significantly lower when the mothers were previously vaccinated. According…
Published on January 12, 2024
People with long COVID are likely to have immune cells showing signs of chronic inflammation and other unusual characteristics, according to a new study by scientists at the Gladstone Institutes and the University of California San Francisco (UCSF). Their findings, which appear in Nature Immunology, support the hypothesis that long…
Published on December 27, 2023
New research from investigators in the U.K. has shown that markers of brain injury are present many months after COVID-19 infection, despite standard blood testing that is normal. The research, published in Nature Communications, helps provide potential therapy pathways for patients that experience cognitive difficulties after recovering from COVID-19 by…