New research from the University of Chicago (UChicago) that examine data from more than 400,000 people has provided new insights of the complex interaction between genetics and the environment in causing variability in common neuropsychiatric disorders. The investigators, whose findings were published in Cell Reports Medicine, are hopeful the information…

A curious phenomenon seen as a result of testing during the COVID-19 pandemic has been the small subset of patients who test positive for the disease long after they have recovered from their infection and also have not been re-exposed to the virus. Two eminent biology professors at the Whitehead…

Cells from individuals with Major Depressive Disorder (MDD) were found to have higher than expected rates of methylation at specific sites on their DNA, when compared to cells from healthy individuals without MDD, according to a multidisciplinary team of University of California-San Francisco (UCSF) scientists, in collaboration with others. Methylation…

Current methods for diagnosing and treating depression remain largely trial and error with no objective measures or blood tests available. But a team led by Alexander Niculescu, M.D., Ph.D., professor of psychiatry at Indiana University, is hoping to bring personalized medicine approach to the condition and other mood disorders. They…

A molecular pathway in Alzheimer’s disease (AD) that could lead to the development of new therapeutic approaches to target the neurodegenerative condition early in its progression was discovered recently by researchers at Case Western Reserve University School of Medicine. The team’s studies, in cells from human AD patients and in…

Rural integrated healthcare delivery network Sanford Health announced it is investing $800,000 in TruGenomix, a provider of behavioral health information and services leveraging genomics and data. Under the terms of the deal, Sanford Health will support TruGenomix by providing its state-of-the-art lab and research capabilities to validate a first-to-market patented…

Genomind said today it will offer its Genomind Professional PGx Express mental health genetic tests at the pharmacies of all ACME Markets Inc. supermarkets in Pennsylvania, expanding a year-and-a-half-old partnership with ACME’s parent company Albertsons. The expanded collaboration—whose value was not disclosed—will bring Genomind’s test to 59 locations nationwide from…

Genomind said today it will launch an enhanced version of its mental health genetic test that will feature a new, more focused report and set of services, all designed to help clinicians better understand a patient’s genetic profile and its implications for mental health treatment. Genomind Professional PGx Express, set…

Researchers studying nearly 147,000 veterans diagnosed with PTSD found that the disorder’s most characteristic symptom—re-experiencing—is associated with eight separate regions of the genome in whites. It is one of the largest genome-wide association studies (GWAS) of its kind to date. “Post-traumatic stress disorder (PTSD) is a major problem among military…

In biology, memories have always had an enigmatic quality that has often eluded researchers studying their formation and retention. Yet now, investigators at the University of Alabama at Birmingham (UAB) have just discovered a novel mechanism that links epigenetic changes in the hippocampus of the rat brain that controls downstream…

Circadian rhythms are regular, daily variations in some of our biological functions and behaviors that are key to health and mental wellbeing. A research team at the University of Glasgow has now identified a potential genetic link between disrupted circadian rhythms and mood disorders, including major depressive disorder (MDD) and…

Stress can lead to anxiety and symptoms of depression, which are caused, in part, by neuroinflammatory processes. Studies in mice by a team at the University of Colorado Boulder have now shown how injections of the bacterium Mycobacterium vaccae can prevent these stress-related inflammatory responses in the brain and reduce stress-induced…

A new study from the Psychiatric Genomics Consortium provides the first molecular evidence that genetic influences play a role in the risk of getting post-traumatic stress disorder (PTSD) after traumatic experiences. The report extends previous findings that showed that there is some shared genetic overlap between PTSD and other mental…

Genomind said today it has completed an $11 million financing with existing shareholders as well as Silicon Valley Bank. “This financing will further fuel Genomind's expansion,” Genomind President and CEO Michael Koffler said in a statement. Based in King of Prussia, PA, Genomind is a developer of genetic tests designed…