A new, point-of-care, electrochemical biosensor that is similar to the lateral flow tests for COVID, can detect the presence of two heart failure biomarkers from a drop of saliva in as little as 15 minutes. The new non-invasive test could move vital screening from the lab to the home and…

A study led by the University of East Anglia (UEA) and Queen Mary University of London in the U.K. shows that the use of magnetic resonance imaging (MRI) to measure pressure in blood vessels around the heart is a good predictor of heart failure risk. The researchers report that higher…

Eli Lilly’s blockbuster diabetes and obesity drug tirzepatide has achieved good results in a Phase III trial of the medication in adults with heart failure with preserved ejection fraction and obesity. The company announced that the joint glucagon-like peptide-1 (GLP-1) and glucose-dependent insulinotropic polypeptide (GIP) agonist met its two primary…

Researchers at the Fujita Health University in Japan report that adding a measure of how well kidneys are filtering blood called estimated glomerular filtration rate (eGFR) to an existing risk measure can more accurately predict sudden cardiac death (SCD) in patients with congestive heart failure. This new measure of risk,…

Researchers from the Brigham and Women’s Hospital, reporting today in the journal JAMA Cardiology, have found links between patients admitted to the hospital for heart failure and a higher risk of kidney disease. The broad-based study, conducted across 372 participating sites, included adults 65 years and older hospitalized for heart…

Researchers based at the University of East Anglia in the U.K. have confirmed that accounting for biological sex when assessing patients for heart failure improves accuracy of diagnosis. The team behind the work, published in the European Heart Journal Open, fine-tuned a method for diagnosing the condition using magnetic resonance…

Results from a Phase III trial of Australian biotech Mesoblast’s mesenchymal precursor cell therapy for heart failure show improved ejection fraction and lower risk of heart attack or stroke in recipients. However, despite these signs of benefit, the study did not meet its primary endpoint, which was time to recurrent…

A new study published yesterday in JACC: Heart Failure by researchers in China shows that social isolation and loneliness are associated with higher rates of heart failure. However, whether a person feels lonely regardless if they are alone or not is more important in determining risk. The new study helps…

Research from the University of Copenhagen shows a link between use of common non-steroidal anti-inflammatory drugs (NSAIDs) and hospitalization for heart failure in patients with type 2 diabetes. In a presentation at the 2022 European Society of Cardiology conference in Barcelona, the Danish team revealed that patients who took ibuprofen…

A study published in the journal Science has challenged the idea that heart failure results from a common disease pathway, suggesting instead that individual genetics comes into play. The research revealed that genetic variants activate specific pathways in cardiomyopathies, some shared and some distinct, that resulted in different cellular landscapes…

The gut-brain connection has been a fertile area of research for some time and has yielded a plethora of insights into how the microbiome can affect cognition and mental health. Now, a systematic review of research from Georgetown University School of Nursing & Health Studies, published in the journal Heart…

Researchers have linked a rare genetic mutation in TTR V142I, which affects mostly people of African descent, to an earlier onset of heart failure and a higher risk of hospitalization. The findings suggest screening for the mutation could lead to faster treatment and improved outcomes, the researchers said. The results…

A type of medication developed for treating diabetes could be also be effective for treating all patients with heart failure, according to researchers from the University of East Anglia. Sodium-glucose co-transporter-2 (SGLT2) inhibitors were first approved to treat type 2 diabetes in 2012 and their main mechanism of action is…

A protein that helps regulate calcium signaling within heart cells could play a key role in preventing chronic heart failure, and could therefore be a good target for drug development, according to an international study led by University of Utah Health scientists. Voltage dependent anion channel 2 (VDAC2) is an…

Microorganisms on the tongue could help diagnose heart failure, according to research presented today on HFA Discoveries, online event from the Heart Failure Association (HFA) of the European Society of Cardiology (ESC). “The tongues of patients with chronic heart failure look totally different to those of healthy people,” said study author…