Precision health company Human Longevity announced it has published data in the journal Proceedings of the National Academy of Sciences(PNAS) demonstrating the ability of integrating whole-genome sequencing, imaging, and metabolomics to help identify adults at risk of specific health conditions. “The goal of precision medicine is to provide a path…

Researchers from dozens of institutions around the world, including the University of Virginia (UVA) School of Medicine, dubbed the GenomeAsia 100K Consortium, have released the results of their examination of the genomes of 1,739 people from 219 different population groups in 64 countries across Asia. The findings from the group…

Researchers in Boston might have hit a gold mine when it comes to cancer treatment—instead of creating new chemical compounds to treat cancer cells, they have taken thousands of pre-existing drug compounds designed to treat other illnesses and screened them for their effects on cancer.  Nearly 50 of these medications…

Eric Dishman, Director of the NIH’s All of Us Research Program The NIH’s All of Us Research Program has chosen the HudsonAlpha Institute for Biotechnology to assess the use of DNA sequencing technologies for diagnosis and treatment of common and rare diseases, under a $7 million…

Although it is recommended for most people to get 7 to 9 hours of sleep, there are some people who can sleep for just 4 to 6 hours and feel well-rested. The team that identified two known human genes that promote this “natural short sleep” have now discovered a third,…

Scientists, for the first time, have mapped the genetic diversity of microbes residing in the human gut and mouth. They found 46 million genes, with at least half of these genes appearing to be unique to each individual—a diversity far exceeding the researchers’ expectations. The study, which was published 12…

RenalytixAI will assess its lead product, the AI-enabled kidney disease diagnostic KidneyIntelX, in more than 3,500 patients with Type II diabetes through a collaboration with University Medical Center Groningen (UMCG) in the Netherlands. The value of the collaboration was not disclosed. The study will be designed to assess how effectively…

David Bentley trained in medical genetics at Guy’s Hospital in London before spending 12 years at the Sanger Centre (now the Wellcome Trust Sanger Institute). There, as Head of Human Genetics and working with director Sir John Sulston and colleagues, he helped set up the British arm of the Human…

An international research team has identified signaling proteins that act in the brain’s hypothalamus to direct the development of neuronal circuits that are involved in weight control. Studies headed by Sadaf Farooqi, PhD, FRCP, FMedSci, a professor at the University of Cambridge, U.K., and Sebastien Bouret, PhD, investigator, endocrinology, diabetes…

By now, we know that the microbiome is important. But, despite all of the attention, exactly what role our commensal bacteria play in human disease remains largely unknown. Two papers were published back-to-back in Nature this week, the largest clinical microbiome studies done to date, that are trying to answer this question.…

The results of studies by researchers at Florida State University College of Medicine suggest that nicotine exposure in men could lead to cognitive deficits in their children and grandchildren. The research found that adding nicotine to the drinking water of male mice led to epigenetic changes in sperm cell genes…

As the U.S. marked the 242nd anniversary of its independence, the mother country also had reason to celebrate. England’s National Health Service commemorated its 70th birthday not with a cake or candles, but with a nicely timed announcement that the 70,000th genome had been sequenced of the 100,000 planned by…

Circadian rhythms are regular, daily variations in some of our biological functions and behaviors that are key to health and mental wellbeing. A research team at the University of Glasgow has now identified a potential genetic link between disrupted circadian rhythms and mood disorders, including major depressive disorder (MDD) and…

Researchers say they have taken a step closer to better understanding how the gut microbiome is formed, changes over time, and is affected by disturbances like antibiotics.  Published June 21 in Molecular Systems Biology, a study (“Deciphering Microbial Interactions in Synthetic Human Gut Microbiome Communities”) by a team from the University of Wisconsin-Madison…

University at Buffalo (UB) scientists say they have developed a new protein analysis tool that could vastly increase the speed and precision with which disease and drug effects are analyzed. Called IonStar, it is the first to provide near-perfect accuracy when quantifying and comparing the abundance of proteins in the bodies of…