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The studies show the prevalence and prognostic potential of these small DNA circles in nearly 15,000 cancers; highlight a novel method of inheritance that overthrows a fundamental understanding of genetics; and identify a potential new therapy currently in clinical trials that can target the circles.
Precision Oncology Today
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5 Key Startups Bringing Digital Pathology Into Focus
Digital pathology is driving precision medicine by turbocharging the analysis of tissue slides. Here are the five top startups turning microscopy into a data...
How Is Artificial Intelligence Changing the Clinical Trials Landscape?
There is no doubt that artificial intelligence (AI) is currently en vogue. Many AI and machine-learning applications are already being deployed in drug discovery and development. Not only can AI process, analyze, and interpret huge datasets, it can also be used for structural drug design and toxicity and efficacy predictions.
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HTAN Members Deliver Wealth of Tumor Biology Insights
Their work covered several diseases including, breast, colon, and pancreatic cancer and included detailed maps pinpointing cells' exact position in tumors—3D cell maps also known as cell atlases.
How p53 Loss Drives Cancer Risk in Ulcerative Colitis
A study in mice and organoid-based models, illuminates the role of the p53 gene in ulcerative colitis.
Mechanisms Behind Myocarditis in Cancer Patients Treated with Immune Checkpoint Inhibitors Found
The research identified specific changes that occur in immune and stromal cells in the heart that underlie the condition and also identified biomarkers in the blood that may indicate whether an individual patient’s myocarditis could lead to death.