Male scientist working in Oxford Nanopore Technologies' genetic sequencing lab

Whole Human Genome Sequenced in Just Over Five Hours in New Record

New Guinness world record for human genome sequencing of less than 6 hours, set at Stanford University using Oxford Nanopore's sequencing technology, helps identify genetic disease in less than 8 hours.
Obsessed Compulsive Perfectionist With Ocd Disorder

Genetic Mutations Linked to Obsessive-Compulsive Disorder Uncovered

Obsessive-compulsive disorder is a psychiatric disorder affecting 1% of the U.S. population, but the underlying causes remain relatively unknown. However, recent research has highlighted potential genetic causes of this psychiatric outcome.
Single-Cell RNA-Seq System

New Spatial Transcriptomic Tool Maps Cell Location and Function in Fine Detail

A tool that can pinpoint the location of detailed immune cell types in the human gut and lymph node, as well as map the fine-grained structure of the mouse brain has been developed by researchers based at the Wellcome Sanger Institute.

Scorpion Therapeutics, AstraZeneca Ink Deal Focused on “Undruggable” Cancer Targets.

The deal provides $75 million upfront for Scorpion and has the potential to generate for the company as much as $1.5 billion in option fees and milestone payments, as well as tiered royalties on net sales ranging from mid-single digit to low-double digits.
T-Cells of the immune System attacking growing Cancer cells

Matching Cancer Therapies to ‘Immune Archetypes’ Could Improve Patient Outcomes

Defining tumors by 'immune archetypes' rather than cancer type could result in cancer immunotherapies being more effective and precise in the future, suggests new research from University of California San Francisco (UCSF).
Triple negative breast cancer cell undergoing retraction and apoptosis

Triple Negative Breast Cancer’s Newest Target: MAPK4

Researchers have discovered that a large subset of triple negative breast cancer expresses significant levels of MAPK4. Their studies showed that eliminating MAPK4 reduced human TNBC cell growth in animal models and sensitized the cells to therapies that block PI3K, a known cancer growth-promoting signaling pathway.

23andMe Launches First Cancer Drug Trial and Gets FDA Nod for Prostate Cancer Marker

The launch of the clinical trial wholly sponsored by 23andMe is a pivotal achievement for the company’s therapeutic development division, which was started in 2015. But in 2020 GSK launched a trial of a drug candidate that came out of its collaboration with 23andMe, which started in 2018.
Senior asian female cancer patient wearing mask talking to doctor

NCCN Publishes Guidance on COVID-19 Vaccination, Antibody Treatments for Cancer Patients

Of note in the recently released updated guidance, was information on the use of a human monoclonal antibody treatment regimen as a preventive measure against contracting COVID-19.
Little girl receives breathing treatment

ASO Cocktail Corrects Severe Cystic Fibrosis Mutation

A combination of splice-switching antisense oligonucleotides could work against a common CFTR mutation that causes a severe form of cystic fibrosis, according to new research.
Genomenon said today it has partnered with Rhythm Pharmaceuticals to create a database of genetic mutations associated with obesity as documented in published studies. Rhythm plans to use the data to better understand rare genetic disorders of obesity. [Visual Mozart/Getty Images]

Genetic Insights into Pathways Behind Obesity Uncovered

A new study by researchers from the department of twin research and genetic epidemiology, King’s College London, and the NIHR BioResource, has revealed genetic pathways underlying obesity.

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newborn baby

Whole Genome Screening for Sick Newborns: Equity Now

The NICUSeq study group has recently reported on their randomized multisite time-delayed trial to test the clinical utility of whole-genome sequencing (WGS) in acutely...
Francis Collins

Francis Collins

Outgoing NIH director remembered for Human Genome Project leadership, withstanding Washington, thinking big, and bringing people together.
Genetic engineering concept. DNA. Gene therapy. Medical technology

Top Precision Medicine Health Systems

Pioneers in the delivery of precision medicine see their programs take hold and influence the next generation of healthcare.
Close up of human biotechnologist testing testing blood for cancer in a laboratory

Catching Cancer Red-Handed

Scientists and clinicians are using blood samples to detect and track these diseases more accurately than ever.

Investigational Medical Products for Rare Diseases: Ethical Concerns and Unresolved Issues with Expanded Access

By Alison Bateman-House, PhD, MPH, MA and Lisa Kearns, MS, MA Introduction Patients who have no therapeutic or diagnostic options available may seek access to investigational...