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Published on April 10, 2024
Investigators at the Murdoch Children’s Research Institute (MCRI) say they have discovered a blood protein biomarker that could help detect which children will experience ongoing concussion symptoms more than two weeks after the initial injury. Reporting in the Journal of Neurotrauma, the MCRI teams demonstrate that levels of the protein…
Published on March 24, 2021
Small, noncoding RNAs (sncRNAs) in saliva can help diagnose concussion in professional rugby players, show results from a University of Birmingham-led study. The research team identified a biomarker panel of sncRNAs that represent a diagnostic signature for sport-related concussion. Reported in the British Journal of Sports Medicine, findings from SCRUM…
Published on November 10, 2020
Testing someone’s saliva for certain micro (mi)RNAs after suspected concussion could help to give a more conclusive diagnosis than currently available tests, according to Penn State University researchers. Concussion, or mild traumatic brain injury, is very common, particularly among young athletes. Accurate diagnosis is important for treatment and recovery and…
Published on April 23, 2018
A fall in the street, a tackle on the gridiron, a bomb blast on the battlefield—any of these events can result in a concussion, or mild traumatic brain injury (mTBI). We already know mTBIs are common, but, they may be even more common that we realize, given our lack of…
Published on January 29, 2018
Oxford BioDynamics (OBD) said today it will partner with Holos Life Sciences to develop noninvasive epigenetic biomarkers associated with sports-related concussions, through a collaboration whose value was not disclosed. The collaboration will use OBD’s EpiSwitch platform to help determine and monitor systemic epigenetic changes and potential physiological reprogramming due to…
Published on March 17, 2017
A research team at the Translational Genomics Research Institute (TGen) recently completed a three-year study of the Arizona State University football program and had created the largest dataset to date of small extracellular RNAs, which are potential biomarkers for diagnosing medical conditions, including concussions. Findings from the new study were…
Published on July 21, 2023
University of Birmingham, England, researchers have launched a new study that will seek to develop a saliva-based early diagnostic for stroke. The research will build off past findings by Antonio Belli, MD, professor of Trauma Neurosurgery at the University of Birmingham’s Institute of Inflammation & Ageing, which could eventually dramatically…
Published on August 22, 2022
Blood tests taken the day of a traumatic brain injury (TBI) can predict which patients are likely to die or survive with severe disability, allowing clinicians to make decisions earlier on possible treatment of TBI, according to a new study. Researchers from Michigan Medicine, the University of California San Francisco,…
Published on July 25, 2022
New biomarkers that distinguish acute from chronic phases of traumatic brain injury (TBI) have been identified by scientists at Arizona State University (ASU). Their work could lead to new therapeutics and diagnostics and also help explain why people who have had TBI are more susceptible to developing neurodegenerative diseases such…
Published on March 30, 2018
In response to injury, cells typically go to work trying to repair the damage. While this healing process is amazingly effective for many tissue types, for various neuronal injuries the repair process is either extremely slow or nonexistent. However now, a new study from investigators at the University of Texas…
Published on February 15, 2018
The FDA has approved the first blood test for mild traumatic brain injury (mTBI), an in vitro diagnostic developed by Banyan Biomarkers to identify patients with suspected concussions. Banyan BTI™ is designed to identify two brain-specific protein biomarkers—Ubiquitin Carboxy-terminal Hydrolase-L1 or UCH-L1 and glial fibrilliary acidic protein (GFAP)—that rapidly appear…