A study funded by the National Institutes of Health (NIH) has found that while there are similar patterns of how long COVID affects virtually every organ system in both younger children and adolescents, younger children were more likely to experience headache, while those older were most likely to suffer from…

In a cohort study of over 10,000 participants with and without prior SARS-CoV-2 infection, a handful of routine clinical laboratory tests were unable to provide a reliable biomarker of SARS-CoV-2 infection’s post-acute sequelae (PASC), also known as “long COVID.” The researchers also showed that all 25 tests failed to provide…

A 2022 study by Ohio State University (OSU) researchers suggesting that blocking a single molecule could protect against severe illness from infection with the SARS-CoV-2 virus has now led to a $15 million grant from the National Institutes of Health (NIH) aimed at finding ways to combat the effects of…

Symptoms associated with long COVID in children differ based on the child’s age, according to a nationwide, multi-site study. The research will be presented at the Pediatric Academic Societies (PAS) 2024 Meeting, held May 3–6 in Toronto.  These findings could help clinicians recognize and manage long COVID in children more…

It is time to stop using terms such as “long COVID” an Australian research team says. Such phrases, they say, imply there is something unique about longer term symptoms associated with COVID. But long COVID, this team maintains, is just a typical post-viral syndrome, indistinguishable from what is seen with…

The National Institutes of Health (NIH) announced Tuesday the launch of two Phase II clinical trials to evaluate the safety and effectiveness of three treatments for adults suffering from long COVID with autonomic nervous system dysfunction. The trials are a part of the NIH’s Researching COVID to Enhance Recovery (RECOVER)…

Research led by the University of Cambridge shows that low iron levels and disrupted iron regulation in the body due to the viral infection may be contributing to long COVID symptoms. Although reports on exact numbers differ, it is thought that up to 30% of all people infected with SARS-CoV-2…

Interferon gamma (IFN-γ) is a potential biomarker for Long COVID fatigue and this finding could be the basis for new therapies for the condition, a University of Cambridge-led study suggests. It’s known that SARS-CoV-2 triggers the production of the antiviral protein IFN-γ, which is associated with fatigue, muscle ache, and…

A National Institutes of Health (NIH) study has found that 5.8 million children have experienced long COVID—symptoms of COVID-19 that have persisted long after the initial infection. The Nationwide research effort called the Researching COVID to Enhance Recovery (RECOVER) Initiative involved 10 pediatric hospital in the U.S., sought to provide…

People with long COVID are likely to have immune cells showing signs of chronic inflammation and other unusual characteristics, according to a new study by scientists at the Gladstone Institutes and the University of California San Francisco (UCSF). Their findings, which appear in Nature Immunology, support the hypothesis that long…

Lower serotonin levels may play a central role in long COVID, and possibly other post-viral cognitive syndromes, according to new research published last week in Cell. The study, led by researchers from the Perelman School of Medicine at the University of Pennsylvania, aims to explain how persistent inflammation after contracting…

New research shows Tau is a possible cause of long COVID “brain fog.” Another study suggests specific genes passed on from Neanderthals confer extra risk of severe COVID-19 symptoms. Studies have shown that contracting COVID-19 can worsen Alzheimer’s disease in patients. The infection may also make people more prone to…

On Monday, the National Institutes of Health (NIH) announced that it opened phase II clinical trials on four potential treatments for long COVID spanning drugs, medical devices, biologics, and other therapies. The trials are a part of the NIH’s Researching COVID to Enhance Recovery (RECOVER) Initiative, a $1.5 billion research…

Computational Biology company PrecisionLife released research that identifies 73 genes that are highly associated with the severe and fatigue dominant forms of long COVID. The results of the study were published on the preprint server medRxiv. The research provides a detailed genetic look into long COVID and also draws commonalities…

New research from the Allen Institute and the Fred Hutchinson Cancer Center provides evidence that an overactive inflammatory response could be a root cause of many cases of long COVID. The study, published today in the journal Nature Communications, details the discovery of a set of molecules associated with inflammation…