821 Results
Sort By:
Published on July 24, 2024
Many breast cancer survivors eligible for genetic counseling and testing are not receiving it according to a new study from the University of Michigan (U-M) Health Rogel Cancer Center. This is increasingly important as cancer treatment and follow up are getting more complex as more new drugs are being introduced.…
Published on July 22, 2024
Drexel University College of Medicine investigators have discovered two drug-like molecules that show early promise to shrink brain tumors caused by metastatic breast cancer. Their research in a mouse model, published in the journal Frontiers in Pharmacology, represents the first successful attempt to target a key metabolic enzyme in brain…
Published on July 17, 2024
Taxanes are often used as chemotherapy for breast cancer, but they can cause side effects in the nervous system, such as foot pain. Researchers at Linköping University in Sweden have now developed a statistical tool that uses sequencing and other data to predict individual risk level for such side effects.…
Published on July 9, 2024
A new AI image tool that selects high-risk women for magnetic resonance imaging (MRI) after negative mammography detects many missed breast cancers, interim findings from a clinical trial suggest. The AI-based system could help offset the extra costs of MRI that have prevented it from being included in national screening…
Published on July 3, 2024
Real-time AI assistance led to much greater efficiency and lower cost, in a study by Dutch researchers of sentinel node biopsies for breast cancer. Sentinel lymph nodes (SNs) are the first lymph nodes to drain lymphatic flow from the tumor. Testing them can be a difficult and time-consuming process. This…
Published on June 28, 2024
Dana-Farber Cancer Institute investigators have found that a year of treatment with an antibody and chemotherapy drug conjugate is highly effective at preventing recurrence of HER2-positive breast cancer in patients with stage 1 disease. The Phase II ATEMPT clinical study, published in the Journal of Clinical Oncology, showed that 97%…
Published on June 5, 2024
Researchers at the University of Copenhagen have shown that using a commercially available AI system can reduce the workload of radiologists by over 33% while improving the overall performance of breast cancer screenings. Mammography exams are routinely used for the early detection of breast cancer, which helps reduce the mortality…
Published on June 4, 2024
Breakthrough cancer drug Enhertu (trastuzumab deruxtecan) appears to have scored another first, this time in a trial of metastatic breast cancer patients with HER2-low and HER2-ultralow tumors. Researchers also presented the first data supporting Enhertu as a first-line treatment in HER2-positive metastatic breast cancer. Further, interim results from the DESTINY-Breast07…
Published on May 29, 2024
Researchers at the Baylor College of Medicine have identified a protein called PKMYT1 as a promising marker for a form of drug-resistant breast cancer, as well as a potential drug target for patients that currently face a very poor prognosis. Up to 80 percent of deaths from breast cancer are…
Published on May 22, 2024
Scientists from King’s College London have made a significant breakthrough in the treatment of aggressive breast cancer by developing a tailored drug that exploits the cancer cells’ weaknesses. This innovative approach, published in Clinical Cancer Research and funded by Breast Cancer Now, offers new hope for patients with triple-negative breast…
Published on May 17, 2024
Researchers at the Hunan Normal University in China have discovered that the expression levels of a protein called retinitis pigmentosa GTPase regulator interacting protein 1-like (RPGRIP1L) may serve as a new prognostic marker for invasive breast cancer (BRCA). Published in The FASEB Journal, the study suggests that RPGRIP1L could provide…
Published on May 15, 2024
Researchers from the Vanderbilt-Ingram Cancer Center identified new genome-wide gene variants at 12 different locations associated with breast cancer in women of African ancestry. They discovered that variants in three of the 12 were associated with triple-negative breast cancer (TNBC). Historically, women of African ancestry have been largely underrepresented in…
Published on May 1, 2024
Scientists have learned that inhibiting the activity of the PRMT5 gene shuts down the growth of metastatic estrogen receptor-positive (ER+) breast cancer cells after they acquired resistance to therapy with CDK4/6 inhibitors. Doctors have increasingly treated metastatic ER+ breast cancers by combining drugs that degrade or block the estrogen receptors on…
Published on April 19, 2024
In a potentially dramatic advance for breast cancer patients, there is now a much better tool for surgeons to tell if they have gotten “all” the cancer out during a lumpectomy. The FDA has approved the LUMISIGHT (pegulicianine) optical imaging agent and the Lumicell Direct Visualization System (DVS), together referred…
Published on April 17, 2024
A retrospective study led by researchers at Washington University School of Medicine in St. Louis and Whiterabbit.ai showed that an artificial intelligence (AI)-based protocol theoretically reduced the number of false positive results from routine mammograms. The study is published in Radiology: Artificial Intelligence. Acknowledging that many AI-based studies in breast…