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Ibuprofen and diclofenac may increase the risk of heart failure in patients with type 2 diabetes according to Danish research.

Researchers from the Center for Clinical Pharmacology at Washington University School of Medicine say they have identified a new target for addiction-free pain treatment.

Researchers have discovered a potential pain insensitivity mutation that codes for a protein known to mitigate the sensory response to heat and the burning sensation caused by chili peppers.

A study of medical cannabis use found that for most oncology patients, pain measures improved significantly, other cancer-related symptoms also decreased, the consumption of painkillers was reduced, and the side effects were minimal.

Studies indicated that kenpaullone acts by boosting levels of an ion transporter gene that is involved in maintaining inhibitory GABA-ergic neurotransmission, with tests in rodent models of nerve injury and bone cancer confirming that the drug effectively reduced pathologic pain-like behavior.