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Published on February 2, 2022
By studying cancer from a network-based perspective rather than a collection of single genes, researchers from Clemson University have characterized uterine cancers in a new way. “Looking at the whole network of genes involved in uterine cancer rather than a variety of single candidate genes will hopefully lead us to…
Published on December 3, 2021
A study led by the University of Cambridge has completed an in-depth cell map of the uterus and endometrial tissue, leading to insights into the cellular basis of different forms of uterine cancer. Published in the journal Nature Genetics, the study is the first in-depth reference map of the uterus…
Published on March 14, 2017
A research team led by investigators at NYU Langone Medical Center's Perlmutter Cancer Center and The University of Texas MD Anderson Cancer Center have managed to chart the complex molecular biology of uterine carcinosarcoma (UCS), a rare and aggressive gynecologic cancer. Findings from this new study, published recently in Cancer…
Published on January 31, 2024
European cancer mortality predictions for 2024 highlight a concerning increase in colorectal cancer deaths among people aged 29–45 years that the researchers suggest is linked to increasing rates of overweight and obesity. For the 14th consecutive year, Carlo La Vecchia, professor of Medical Statistics and Epidemiology at the University of Milan…
Published on September 13, 2023
The American Association for Cancer Research (AACR) released its annual Cancer Progress Report on Wednesday that highlighted advances in cancer treatments and survival while also advocating for continued funding by the US government to sustain progress. “The advances in cancer research, particularly in the last two decades, have been breathtaking,”…
Published on September 12, 2023
Moderna and Immatics are collaborating to “pioneer novel and transformative therapies for cancer patients with high unmet medical needs,” in a deal worth potentially $1.7B+. They will combine Immatics’ T cell receptor (TCR) platform with Moderna’s mRNA technology, and span modalities including bispecifics, cell therapy, and cancer vaccines. Cambridge-based Moderna…
Published on August 17, 2023
A multisite study published today in the Clinical Cancer Research, a journal of the American Association for Cancer Research (AACR) shows that a commonly prescribed anxiety drug is linked with worse outcomes in pancreatic cancer patients and shorter progression-free survival (PFS). The drug, benzodiazepine lorazepam, sold under the trade name…
Published on August 4, 2023
Research led by the American Cancer Society shows that among cancer survivors, Black and Hispanic individuals who have a second primary cancer have poorer survival than their White counterparts in the U.S. In a study including more than 200,000 people, Black and Hispanic patients were 21% and 10% more likely…
Published on June 14, 2023
Obesity has been previously linked to an increased risk of cancer, but most studies have not differentiated the risks between male and female patients. A prospective study of more than 400,000 UK Biobank participants, carried out by researchers at Uppsala University, has now found that both overall fat accumulation and…
Published on August 31, 2022
Ambry Genetics has announced findings from a large-scale study that showed paired RNA and DNA genetic testing detected elusive pathogenic variants in 1 of every 950 patients that were missed by DNA testing alone. The findings, were published in Genomic Medicine. The researchers say that concurrent RNA and DNA testing…
Published on January 7, 2022
Pembrolizumab appears effective for aggressive endometrial (uterine) cancer, according to results from an international Phase II clinical trial led by researchers at The Ohio State University Comprehensive Cancer Center (OSUCCC). This immunotherapy is currently approved by the U.S. Food and Drug Administration (FDA) to treat several other forms of cancer.…
Published on November 19, 2021
Blood-based metabolic signatures may predict whether women with ovarian or uterine cancer will respond well to platinum-based chemotherapy, according to a study by researchers in the Department of Gynecology at the Federal University of São Paulo’s Medical School (EPM-UNIFESP) in Brazil, in partnership with colleagues at the University of California…
Published on April 9, 2021
When people think of what causes cancer, they probably think of smoking, too much sun, maybe even diet. Various carcinogens do drive genetic mutations that set off cancers. In some cases, though, someone’s genes at birth—the ones that make up a person’s germline genome—can cause cancer. According to Prasanth Reddy,…
Published on October 6, 2020
The way cancer mutations accumulate in the genome depends on both the 3D structure of the chromosome and the factor that is causing the mutation, shows research from the University of Texas MD Anderson Cancer Center. The scientists believe this information could help to guide treatment better, as well as…
Published on July 29, 2020
Thrive Earlier Detection said today it has raised $257 million in Series B financing toward advancing its CancerSEEK liquid biopsy test CancerSEEK is a a DNA- and protein-based liquid biopsy designed to detect cancer by analyzing eight tumor specific genomic mutations in circulating tumor DNA (ctDNA) and cancer-associated protein biomarkers…