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Published on December 15, 2023
People who received mRNA vaccines against SARS-CoV-2 after a COVID-19 infection produced a large number of protective CD8 T cells, researchers at the University of Washington School of Medicine in Seattle have found. Their work was published last week in Nature Immunology. The finding may explain why people who have…
Published on November 14, 2023
Data from a new study by researchers at Mass General Brigham found that 20% of patients who were treated for severe symptoms had COVID-19 return after being treated with Paxlovid after an initial recovery and negative test result. Only 2% of patients who recovered from COVID-19 and didn’t take Paxlovid…
Published on November 6, 2023
The first mice that display a humanlike form of COVID-19 have been engineered, according to a study published online November 1 in Nature. The authors, from NYU Grossman School of Medicine, created a strain of mice with human genetic material for angiotensin-converting enzyme 2 (ACE2)—a receptor through which SARS-CoV-2 enters…
Published on October 25, 2023
The Global Coalition for Adaptive Research (GCAR) today announced clinical trial results of vitamin C and simvastatin to treat severely ill patients with COVID-19. Simvastatin was shown to have a high probability (96%) of improving outcomes (a combination of survival and length of time patients need support in an intensive…
Published on October 24, 2023
Research led by Weill Cornell Graduate School of Medical Sciences shows that certain species of gut fungi, notably Candida albicans, increase in numbers during serious COVID-19 infection and appear to contribute to the excessive and damaging inflammation seen in these patients. High levels of immunoglobulin G (IgG) antibodies against fungi…
Published on October 23, 2023
Lower serotonin levels may play a central role in long COVID, and possibly other post-viral cognitive syndromes, according to new research published last week in Cell. The study, led by researchers from the Perelman School of Medicine at the University of Pennsylvania, aims to explain how persistent inflammation after contracting…
Published on October 16, 2023
Codagenix’s nasal vaccine for COVID-19 delivered positive results in a Phase I trial, according to a presentation at IDWeek’s 2023 annual meeting last week. In tandem, the U.S. awarded almost $20M in funding for nasal COVID-19 development. CastleVax and Codagenix, the only two companies that have delivered Phase I results…
Published on September 29, 2023
SARS-CoV-2 increases the risk of heart attack and stroke by causing fatty plaque in cardiac arteries to become highly inflamed, according to a new study funded by the National Institutes of Health. The findings, published in the journal Nature Cardiovascular Research, may help explain why certain people who get COVID-19 have a greater chance of developing…
Published on September 28, 2023
COVID-19 is still a public health challenge. New variants are emerging and hospitalizations are rising for the first time in several months. As a result, countries are scrambling to prepare in case the pandemic roars back. To support global monitoring and control, the World Health Organization (WHO) has published a…
Published on September 25, 2023
The antiviral drug molnupiravir, used extensively to treat SARS-CoV-2 infection, induces genetic mutations in the virus that could lead to new variants emerging, according to new research led by the Francis Crick Institute in London. So far there is no direct evidence of molnupiravir use leading to a new and…
Published on September 22, 2023
Analysis of cough sounds in early COVID-19 can predict severe pneumonia risk, according to research led by IBEC and Hospital del Mar, with collaboration from the Universitat Politècnica de Catalunya (UPC), CIBER-BBN and CIBERES. Their study was published this week in the European Respiratory Journal Open Research, ERJ Open Research. The team…
Published on September 20, 2023
New research shows Tau is a possible cause of long COVID “brain fog.” Another study suggests specific genes passed on from Neanderthals confer extra risk of severe COVID-19 symptoms. Studies have shown that contracting COVID-19 can worsen Alzheimer’s disease in patients. The infection may also make people more prone to…
Published on August 1, 2023
On Monday, the National Institutes of Health (NIH) announced that it opened phase II clinical trials on four potential treatments for long COVID spanning drugs, medical devices, biologics, and other therapies. The trials are a part of the NIH’s Researching COVID to Enhance Recovery (RECOVER) Initiative, a $1.5 billion research…
Published on July 19, 2023
New findings from researchers at the University of California, San Francisco (UCSF) demonstrate that a mutation in one of the genes coding for human leukocyte antigen (HLA) may explain why some people exposed to COVID-19 don’t become sick. The mutation appears to allow T cells to identify the virus very…
Published on July 18, 2023
Computational Biology company PrecisionLife released research that identifies 73 genes that are highly associated with the severe and fatigue dominant forms of long COVID. The results of the study were published on the preprint server medRxiv. The research provides a detailed genetic look into long COVID and also draws commonalities…