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Inside Precision Medicine New Method Shows Promise to Deliver Therapeutics Across the Blood-Brain Barrier

Nucleic acid therapeutics

Astrocytes, which may help form the blood-brain barrier
News & Features

New Method Shows Promise to Deliver Therapeutics Across the Blood-Brain Barrier

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Molecule of mRNA, illustration
Precision Medicine

Innovative Packaging of mRNA Therapeutics Improves Their Delivery and Speeds Development

Anita Chakraverty
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Illustration of red blood cells moving through clogged artery to indicate cholesterol build up as a result of familial hypercholesterolemia and atherosclerosis, which can be caused by high levels of lipoprotein(a) or Lp(a).
News & Features

Lipoprotein(a) Lowering Draw Between Lilly and Silence

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Man with Duchenne muscular dystrophy sitting in a motorized wheelchair using power controller with degenerated hands
News & Features

Sizing it Up: New Method Enables Large Gene Delivery to Treat Muscular Dystrophies

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Degradation of a motor neuron presented as an illustration. Shows the kind of damage seen in ALS, which may be worsened by alpha-5 integrin
News & Features

Trace Neuroscience Launches with $101M and a Potential Genomic ALS Target

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muscle fiber
News & Features

In Conversation with Frank Gleeson

Helen Albert
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Image showing pathological phosphorylation (yellow) of Tau proteins (red-orange) leads to disintegration of microtubuli in the neuron axon an aggregation of the tau proteins. The transport of synaptic vesicles (orange-blue) is interrupted. This is just part of the disease pathology seen in a single cell map of the Alzheimer's disease brain.
News & Features

New Therapy Shows Promise in Targeting Tau Tangles in Alzheimer’s Disease

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Cancer Gene
News & Features

New DNA-Targeting Screening Technique for Cancer Therapies

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Image of a heart with a DNA double helix in front of it to indicate cardiovascular disease and the impact of transthyretin amyloid cardiomyopathy (ATTR-CM) which can be treated with vutrisiran.
News & Features

Alnylam’s Vutrisiran Gets Good Results for Cardiac Amyloidosis

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ribonicleic acid chain from which can be used to make RNA silencing treatments for conditions such as congenital melanocytic nevus syndrome
News & Features

RNA Silencing Therapy Could Help Treat Rare Skin Condition

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