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Published on April 16, 2024
Add multiple sclerosis to the list of conditions the new weight loss drugs may help treat. Novel diabetes drugs like Ozempic and Wegovy initially showed promise in weight loss and have since been marketed and widely used for this indication. However, a new study based on real world data (RWD)…
Published on February 28, 2024
Scientists at the University of Exeter and at King’s College London report that a novel genetic risk tool may help prevent young people from going blind and predict patients who will progress to multiple sclerosis (MS) earlier. The findings published in Nature Communications have shown for the first time that combining…
Published on January 9, 2024
A combination of only 11 proteins can be used to predict long-term disability outcomes in multiple sclerosis (MS), according to researchers from Linköping University, the Karolinska Institute, and the University of Skövde. This set of proteins could be used, they suggest, to tailor treatments for individuals based on expected severity…
Published on November 7, 2023
In a new study, researchers at the University of California, San Francisco (UCSF), say they have discovered that a known biomarker for nerve damage can predict a worsening of disability in multiple sclerosis (MS) patients, one to two years before it occurs. MS is an immune-mediated disease of the central…
Published on September 12, 2023
Traditional vaccines work by teaching the immune system to recognize a virus or bacteria that needs to be attacked. Now, researchers at the University of Chicago’s Pritzker School of Molecular Engineering (PME) say they have developed a new vaccine that does just the opposite by removing the immune system’s memory…
Published on August 9, 2023
An engineered probiotic could be one answer to treating autoimmunity in the brain in multiple sclerosis (MS) patients, suggests research led by Brigham and Women’s Hospital and Harvard University. “Engineered probiotics could revolutionize the way we treat chronic diseases,” said lead investigator Francisco Quintana, a professor at Harvard and a…
Published on December 30, 2022
TG Therapeutics, scored a win this week, announcing the U.S. Food and Drug Administration (FDA) approved BRIUMVI (ublituximab-xiiy), for the treatment of relapsing forms of multiple sclerosis (MS). While the drug enters a market that is crowded, it is a growing one—MS therapeutics are worth over $25 billion now, and expected to…
Published on December 7, 2022
Results from a proteome-wide association study led by Sichuan University pinpoint three genes containing mutations that could be causative for multiple sclerosis. Multiple sclerosis (MS) is a chronic neurological condition affecting around one million people in the U.S., where progressive damage to the outer “myelin sheath” of the neurons causes…
Published on April 29, 2022
Four new target molecules of potential significance for future personalized treatment of multiple sclerosis (MS) have been identified by researchers at the Karolinska Institute in Sweden. “MS is an inflammatory disease of the central nervous system (CNS), in which pathological T cells, likely autoimmune, play a key role,” the researchers…
Published on April 22, 2022
Biomarker analysis company Quanterix announced today that its Simoa neurofilament light chain (NfL) plasma test has been granted Breakthrough Device designation by the FDA to aid in assessing the likelihood of disease activity in patients diagnosed with relapsing-remitting Multiple sclerosis (RRMS). While Breakthrough Device designation is intended to allow patients…
Published on February 18, 2022
A new study from the University of Zurich analyzed molecular signatures of circulating immune cell types in identical (monozygotic) twins, where both siblings carry the same genetic and early-life environmental risks, but only one sibling is affected by multiple sclerosis (MS), to investigate the interactions between environmental and genetic factors…
Published on January 27, 2022
Web-like DNA structures called neutrophil extracellular traps (NETs) can trigger the onset of autoimmune diseases such as multiple sclerosis (MS), according to research from the Australian National University (ANU). In a study published in the journal Nature Communications the researchers demonstrate that NETs activate T cells and enhance the differentiation of…
Published on January 14, 2022
A new study lends much support to the link between Epstein-Barr Virus (EBV) and multiple sclerosis (MS). Using data from more than ten million United States military recruits monitored over a 20-year period, 955 of whom were diagnosed with MS during their service, lead author Kjetil Bjornevik and colleagues tested the hypothesis…
Published on May 21, 2020
Research suggests that high levels of a nerve protein in the blood can predict worsening disability in people with multiple sclerosis. “In a disease like multiple sclerosis that is so unpredictable and varies so much from one person to the next, having a noninvasive blood test like this could be…
Published on October 19, 2016
At the American Society of Human Genetics (ASHG) 2016 Annual Meeting in Vancouver, B.C., researchers from Harvard Medical School, the Broad Institute, and Brigham and Women's Hospital (BWH) presented data of a large-scale, genome-wide analysis of more than 110,000 samples. The researchers reported that the data, which had been collected by the…