chronic pain - search results

Research from a National Institutes of Health-funded study that collected pain-related data from within the brains of small cohort of patients has identified a specific area of the brain and related biomarkers associated with chronic pain.

A collaborative Canadian study has discovered sex-specific mechanisms of chronic pain processing in neurons of the spinal cord that are conserved across species from rodents to humans, a finding which could lead to the development of more personalized therapies for this indication in the future.

The genome-wide association study analyzed samples of 158,000 individuals of European ancestry including 29,000 with chronic back pain

Researchers have discovered a potential pain insensitivity mutation that codes for a protein known to mitigate the sensory response to heat and the burning sensation caused by chili peppers.

Confo Therapeutics, which specializes in targeting G-protein coupled receptors (GPCRs), has announced a worldwide licensing agreement with Eli Lilly a non-opioid pain medication.

Ibuprofen and diclofenac may increase the risk of heart failure in patients with type 2 diabetes according to Danish research.

Digging deeper into biology could produce targeted drugs and diagnostics to treat a collection of life-long conditions.

Comprehensive Genomic Profiling (CGP) has the promise to be a game-changer to inform precision oncology, but the hurdles remain. 

Late stage results for Mesoblast's rexlemestrocel-L allogenic cell therapy look promising for patients with lower back pain due to degenerative disc disease.

Studies indicated that kenpaullone acts by boosting levels of an ion transporter gene that is involved in maintaining inhibitory GABA-ergic neurotransmission, with tests in rodent models of nerve injury and bone cancer confirming that the drug effectively reduced pathologic pain-like behavior.