Last week, the FDA approved BridgeBio’s Attruby (acoramidis) for adults with Transthyretin amyloid cardiomyopathy (ATTR-C)—a rare disease that can cause serious heart problems and death. Attruby is the first and only approved treatment with a label specifying near-complete stabilization of Transthyretin (TTR). The company also said Attruby demonstrated the most…

A new study suggests doctors can use information from their patients’ wearable devices to monitor the effectiveness of medications they prescribe to treat heart disease. Researchers at the University of Birmingham used consumer wearable devices that monitor heart rate and physical activity to compare responses to two treatments for atrial…

Researchers at the Icahn School of Medicine at Mount Sinai have made significant strides in understanding the genes behind of coronary artery disease (CAD) through the use of an advanced artificial intelligence tool. Published in Nature Genetics, their study identified rare coding variants in 17 genes that provide new insights…

Heart disease in women is underdiagnosed compared to men. Now, more accurate cardiovascular risk models for women have been developed by U.S. and Netherlands researchers using a dataset of more than 20,000 participants in the UK Biobank. This team also quantified the underdiagnosis of heart disease in women. They say…

Coronary artery disease and major depression may be genetically interconnected via inflammatory pathways, according to researchers at the Vanderbilt University Medical Center (VUMC) and the Massachusetts General Hospital (MGH). They used transcriptome-wide association scans to map single nucleotide polymorphisms involved in regulating the expression of genes associated with both CAD…

Researchers from the Broad Institute of MIT and Harvard together with Massachusetts General Hospital investigators have identified specific species of bacteria in the gut that consume bacteria to help lower cholesterol and decrease the risk of heart disease. The research, published Tuesday in the journal Cell, adds to the list…

Ohio State University researchers have published a study that shows treating people with heart disease who have symptoms of depression and anxiety significantly decreased visits to the emergency room and rehospitalizations. The research, published today in the Journal of the American Heart Association, noted that depression and anxiety are common…

Common cardiovascular-related pregnancy complications may result in worse future heart health for the child as well as the mother, a new study suggests. This large, collaborative study found signs of higher risk of cardiovascular disease and stroke in about half of children born after a pregnancy that featured hypertension or…

Even people with moderately elevated low-density lipoprotein cholesterol (LDL-C) have higher risk of heart disease if they also had a variant for familial hypercholesterolemia (FH), according to new research. The long-term study included over 20,000 patients and reinforces the value of genetic testing for this condition. The study was published…

A study led by Children’s National Hospital in Washington shows that artificial intelligence (AI) is able to diagnose early-stage rheumatic heart disease as accurately as expert cardiologists based on an analysis of echocardiograms. Rheumatic heart disease kills almost 300,000 people per year, mostly in low- and middle-income countries. It occurs…

Results from a UK Biobank study show people who develop coronary heart disease (CHD) have increased dementia risk in later life particularly those who develop heart disease before the age of 45 years. Led by the Chinese Academy of Medical Sciences and Peking Union Medical College in Beijing, China, the…

Biomedical engineers from Duke University report they have developed a method that combines smartwatch data with a digital twin framework that can predict a patient’s risk of developing heart disease or having a heart attack. The method can digitally mimic an entire week’s worth of an individual’s heartbeat, far eclipsing…

Walgreens and the Cardiovascular Research Foundation (CRF) announced a collaboration on a population-based clinical trial that seeks to quantify the prevalence of valvular heart disease (VHD) in older Americans. Under the terms of the deal, Walgreens will leverage its broad national presence to help recruit potential trial participants employing its…

Heart health experts are declaring the overlapping effects of obesity, Type 2 diabetes, chronic kidney disease, and cardiovascular disease as a new syndrome—cardiovascular-kidney-metabolic syndrome, or CKM. This change, they say, is prompting rethinking of how they predict long-term cardiovascular risks. A presidential advisory from the American Heart Association (AHA), published Monday in the…

A new drug could become the first treatment for Lipoprotein(a), a form of cholesterol that increases the risk of heart attack and stroke, as announced this week at the European Society of Cardiology Congress in Amsterdam and published in JAMA. The Phase I study included 114 patients, and the lead investigator was…