DNA and RNA molecules

Graphene Hydrogel Could Help mRNA Vaccine Target Cancer More Effectively

A specialized hydrogel can not only encapsulate and protect mRNA cancer vaccines from being broken down in the body, but can also target lymph nodes to activate immune cells, shows early stage research.
Fatty liver, conceptual illustration

TGen Study Pinpoints Biomarkers for Non-Alcoholic Fatty Liver Disease

The researchers identified differences in DNA methylation (DNAm) that accurately predicted different stages of liver fibrosis in as many as 94% of patients with non-alcoholic fatty liver disease (NAFLD), according to the study published in the journal Clinical Epigenetics.
Corona Virus Covid-19 Medical Vaccine Concept.

Cancer Vaccine Effectiveness May Lie in Reawakening Dormant T-Cells

MIT researchers revealed that vaccinating against certain neoantigens can boost overall T-cell response by reawakening dormant T cell populations that target those proteins and help shrink tumors in mice.
Coronavirus, virus, flu, bacteria close-up. Abstract 3D rendered illustration

COVID-19 Antibodies Derived from Llamas Show Therapeutic Potential

The nanobodies, which bind tightly to the SARS-CoV-2 virus, neutralizing it in cell culture, could provide a cheaper and easier to use alternative to human antibodies taken from patients who have recovered from COVID-19.
Image on screen of cancer screen. Artificial intelligence (AI) can be used in software that helps a pathologist interpret features of cancer in digitized images of samples.

AI For Cancer Detection: Ready for Prime Time or Caution Advised?

AI-based cancer imaging diagnostics have improved enormously over the last few years, with some programs already in use in the clinic, but researchers advise caution with more widespread rollout until more large-scale testing is completed.
Image of researchers in a lab adding samples to a Helix sequencing machine.

Helix, MUSC to Launch Population Health Genomics Initiative in South Carolina

A new genomics program in South Carolina will enroll 100,000 volunteers over 4 years who will undergo exome testing to provide useful health information to the patients and their clinicians from the start, while also contributing to medical research.
corona virus 1

COVID-19 Antiviral Candidate Targeting RNA Replicase Developed

U.S. researchers have developed an antiviral candidate drug targeting iron-sulfur clusters needed for SARS-CoV-2 RNA replicase to function properly and for the virus to reproduce successfully.
RNA Polymerase II transcribing DNA, illustration

Newly Discovered Checkpoint Mechanism Fine Tunes Gene Transcription

Disruption of the mechanism leads to unrestricted gene transcription and is implicated in cancer, say the scientists. The study points to new opportunities for therapeutic intervention by demonstrating the anti-cancer effect of a new combination treatment in preclinical models of solid and hematopoietic malignancies.
Sickle cell anemia

Mitochondrial DNA Triggers Inflammation in Sickle Cell Anemia Patients

Mitochondrial DNA fragments in the blood are a trigger for inflammation in people with sickle cell disease, suggests new research. The red blood cells of people with this chronic condition seem to accumulate mitochondria, which are absent from healthy blood cells. When these organelles break up their DNA is also broken up and found circulating in the blood.
Gut-brain connection or gut brain axis. Concept art showing a connection from the gut to the brain. 3d illustration.

Gut Microbes That Influence Neurological Disorders May Inspire New Therapies

Researchers at the Baylor College of Medicine report that they have found that microbes in the gut may contribute to certain symptoms associated with complex neurological disorders, which also suggests that microbe-inspired therapies may one day help to treat them.