A study from Johns Hopkins University, published in Biophotonics Discovery, examined how skin tone affects the accuracy of photoacoustic imaging (PAI), a technology gaining traction in breast cancer diagnostics, especially in situations where traditional mammography is insufficient. The study shows how image reconstruction methods and laser wavelengths influence the visibility…

A groundbreaking study from Harvard Medical School researchers should change long-held beliefs about the BRCA1 gene and its role in breast cancer. Researchers have discovered that even a single defective copy of the BRCA1 gene can make breast cells more susceptible to cancer, without the need for a second genetic…

A new study from investigators from the Clínica Universidad de Navarra in Spain shows that approximately 40% of postmenopausal hormone receptor-positive breast cancer cases may be associated with excess body fat. This finding, published in the Journal of Epidemiology & Community Health, shows that the attributable effects of excess body…

A recent study from investigators at the UCLA Health Jonsson Comprehensive Cancer Center has found that common treatments for breast cancer—chemotherapy, radiation, and surgery—may contribute to accelerated biological aging in survivors. The research, published in the Journal of the National Cancer Institute, demonstrates that markers of cellular aging such as…

Commercially available artificial intelligence (AI) algorithms that help radiologists immediately detect breast cancer at mammography screening can also highlight women who are at risk years before their eventual diagnosis, research indicates. The findings, reported in JAMA Network Open, could offer a pathway for personalized screening that may lead to the…

Researchers from the Mass General Brigham have revealed that Black women face a higher risk of dying from breast cancer than white women across all tumor subtypes. The meta-analysis, published in the Journal of Clinical Oncology, shows that Black women’s risk of death varies from 17% to 50% higher depending…

A 10-year study from researchers at the Yale School of Medicine has demonstrated that use of digital breast tomosynthesis (DBT) increases breast cancer detection rates and significantly reduces the rate of advanced cancer than does the standard screening method of two-dimensional digital mammography. Mammography has long been considered the gold…

Researchers at the Dana-Farber Cancer Institute, reporting at the European Society of Medical Oncology Congress in Barcelona, say that an antibody-drug conjugate that delivers chemotherapy directly to the tumor site has shown “impressive” activity against HER2-positive breast cancer that has spread to the brain. The findings, according to the study…

Researchers at Rockefeller University have uncovered a crucial link between sensory neurons and the metastasis of breast cancer. Published in Nature, their work reveals that sensory nerves within breast tumors secrete a neuropeptide that significantly promotes cancer growth and spread. This discovery suggests that targeting this neuro-cancer crosstalk may help…

Many breast cancer survivors eligible for genetic counseling and testing are not receiving it according to a new study from the University of Michigan (U-M) Health Rogel Cancer Center. This is increasingly important as cancer treatment and follow up are getting more complex as more new drugs are being introduced.…

Drexel University College of Medicine investigators have discovered two drug-like molecules that show early promise to shrink brain tumors caused by metastatic breast cancer. Their research in a mouse model, published in the journal Frontiers in Pharmacology, represents the first successful attempt to target a key metabolic enzyme in brain…

Taxanes are often used as chemotherapy for breast cancer, but they can cause side effects in the nervous system, such as foot pain. Researchers at Linköping University in Sweden have now developed a statistical tool that uses sequencing and other data to predict individual risk level for such side effects.…

Real-time AI assistance led to much greater efficiency and lower cost, in a study by Dutch researchers of sentinel node biopsies for breast cancer. Sentinel lymph nodes (SNs) are the first lymph nodes to drain lymphatic flow from the tumor. Testing them can be a difficult and time-consuming process.  This…

Dana-Farber Cancer Institute investigators have found that a year of treatment with an antibody and chemotherapy drug conjugate is highly effective at preventing recurrence of HER2-positive breast cancer in patients with stage 1 disease. The Phase II ATEMPT clinical study, published in the Journal of Clinical Oncology, showed that 97%…

Researchers at the Hunan Normal University in China have discovered that the expression levels of a protein called retinitis pigmentosa GTPase regulator interacting protein 1-like (RPGRIP1L) may serve as a new prognostic marker for invasive breast cancer (BRCA). Published in The FASEB Journal, the study suggests that RPGRIP1L could provide…