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Published on May 15, 2024
Researchers based at the University of East Anglia in the U.K. have confirmed that accounting for biological sex when assessing patients for heart failure improves accuracy of diagnosis. The team behind the work, published in the European Heart Journal Open, fine-tuned a method for diagnosing the condition using magnetic resonance…
Published on January 11, 2024
Physicians at cancer research and treatment organization City of Hope have published new results from a study that shows the blood vessel relaxing medication carvedilol may benefit childhood cancer survivors who are at risk of developing heart failure. Heart failure developed in later years can be a serious complication for…
Published on November 29, 2023
Cardiologists and radiation oncologists at Washington University School of Medicine have repurposed radiation therapy, a conventional approach used against cancer, to target patients with ventricular tachycardia. Heart failure, a condition affecting approximately 6.7 million American adults, is characterized by the heart’s gradual loss of its ability to supply the body…
Published on October 18, 2023
Researchers from the Max Delbrück Center for Molecular Medicine and the Charité University Hospital in Berlin, Germany have uncovered the PDM16 gene as a previously unknown genetic factor that increases the risk of congenital heart failure in women. Heart failure, characterized by the heart’s inability to pump blood effectively, is…
Published on March 15, 2023
A clinical study led by scientists at Karolinska Institute and Karolinska University Hospital in Sweden reveals how the hunger hormone ghrelin can increase cardiac pump function in patients with heart failure. According to the Heart Failure Society of America, nearly seven million Americans over the age of 20 suffer from…
Published on February 28, 2023
Results from a Phase III trial of Australian biotech Mesoblast’s mesenchymal precursor cell therapy for heart failure show improved ejection fraction and lower risk of heart attack or stroke in recipients. However, despite these signs of benefit, the study did not meet its primary endpoint, which was time to recurrent…
Published on February 2, 2023
A new study published yesterday in JACC: Heart Failure by researchers in China shows that social isolation and loneliness are associated with higher rates of heart failure. However, whether a person feels lonely regardless if they are alone or not is more important in determining risk. The new study helps…
Published on September 30, 2022
A new partnership to study heart failure with preserved ejection fraction (HFpEF) is being launched by the National Institutes of Health and several private corporations. The Foundation for the National Institutes of Health (FNIH) and the National Heart Lung and Blood Institute (NHLBI) will work with partners that include Bayer…
Published on August 24, 2022
Research from the University of Copenhagen shows a link between use of common non-steroidal anti-inflammatory drugs (NSAIDs) and hospitalization for heart failure in patients with type 2 diabetes. In a presentation at the 2022 European Society of Cardiology conference in Barcelona, the Danish team revealed that patients who took ibuprofen…
Published on August 5, 2022
A study published in the journal Science has challenged the idea that heart failure results from a common disease pathway, suggesting instead that individual genetics comes into play. The research revealed that genetic variants activate specific pathways in cardiomyopathies, some shared and some distinct, that resulted in different cellular landscapes…
Published on June 21, 2022
The gut-brain connection has been a fertile area of research for some time and has yielded a plethora of insights into how the microbiome can affect cognition and mental health. Now, a systematic review of research from Georgetown University School of Nursing & Health Studies, published in the journal Heart…
Published on December 9, 2021
Researchers have linked a rare genetic mutation in TTR V142I, which affects mostly people of African descent, to an earlier onset of heart failure and a higher risk of hospitalization. The findings suggest screening for the mutation could lead to faster treatment and improved outcomes, the researchers said. The results…
Published on December 1, 2021
A type of medication developed for treating diabetes could be also be effective for treating all patients with heart failure, according to researchers from the University of East Anglia. Sodium-glucose co-transporter-2 (SGLT2) inhibitors were first approved to treat type 2 diabetes in 2012 and their main mechanism of action is…
Published on July 28, 2021
A protein that helps regulate calcium signaling within heart cells could play a key role in preventing chronic heart failure, and could therefore be a good target for drug development, according to an international study led by University of Utah Health scientists. Voltage dependent anion channel 2 (VDAC2) is an…
Published on June 24, 2020
Microorganisms on the tongue could help diagnose heart failure, according to research presented today on HFA Discoveries, online event from the Heart Failure Association (HFA) of the European Society of Cardiology (ESC). “The tongues of patients with chronic heart failure look totally different to those of healthy people,” said study author…