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Published on May 12, 2017
Offering Includes Whole Genome Sequencing and Full Body MRI to Give Insight into Cancer, Cardiovascular, Metabolic and Neurological Disease Risk Human Longevity, which focuses on a genomics-based approach to unlocking insights into human health launched Health Nucleus X (HNX) a pilot program designed to provide individuals and their physicians actionable…
Published on April 14, 2017
An adapted CRISPR protein that targets RNA can serve as a rapid, inexpensive, and sensitive diagnostic tool say researchers from the Broad Institute of MIT and Harvard, the McGovern Institute for Brain Research at MIT, the Institute for Medical Engineering & Science at MIT, and the Wyss Institute for Biologically…
Published on March 22, 2017
Liquid biopsies in oncology initially focused on detecting and analyzing the numbers and types of circulating tumor cells (CTCs) in the blood, but more recently many researchers have come to include analysis of cell-free DNA (cfDNA) or circulating tumor DNA (ctDNA). cfDNA testing was first used in the United States…
Published on March 21, 2017
Like many hospitals affiliated with medical schools and medical research, doctors at Vidant Health in Eastern North Carolina had been dabbling in the use of liquid biopsies, to both ease the burden of invasive tissue biopsy procedures, and to learn about how well it could provide relevant information to guide…
Published on February 14, 2017
Salk Institute researchers have developed a computational algorithm that integrates two different data types to make locating key regions within the genome more precise and accurate than other tools. The new method, detailed recently in PNAS through an article entitled “Improved regulatory element prediction based on tissue-specific local epigenomic signatures,”…
Published on November 28, 2016
Scientists at Dartmouth's Norris Cotton Cancer Center (NCCC) say they have identified the functional role of two distinct DNA modifications in glioblastoma (GBM) tissues. The signature of one of these pattern disruptions, in particular, 5-hydroxymethylcytosine (5hmC), had a particularly strong association with patient survival. GBM is a rare but deadly…
Published on May 13, 2016
Gliomas are the most common malignant brain tumors in humans, constituting about 30% of all brain and central nervous system tumors and 80% of all malignant brain tumors. Gliomas are very severe human brain tumors that are rarely curable. Interestingly, these tumors are strikingly similar in dogs and humans. Moreover,…
Published on February 23, 2016
Lipidomics, the large-scale analysis of cellular lipids, is not only enriching the discipline of systems biology, it is also contributing to the development of new biomarkers. Yet for all the structural and mechanistic insights it is capable of providing, lipidomics continues to struggle with a blind spot. It has trouble…