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Published on February 12, 2025
Scientists from the German Cancer Research Center (DKFZ) and ShanghaiTech University have developed a cutting-edge method for growing patient-specific brain tumor organoids that closely replicate the structure and molecular characteristics of the original tumor. This breakthrough could revolutionize personalized medicine by enabling doctors to test therapies on a patient’s tumor…
Published on February 11, 2025
There can be little doubt that artificial intelligence (AI) is having a moment. From big wins at this year’s Nobel prizes to AI summaries topping search engine results, its reach stretches from cutting-edge science to the most mundane of Google answers. Physicians have been particularly enthusiastic about the technology, likening…
Published on February 10, 2025
The use of artificial intelligence (AI) is burgeoning in the drug discovery space as pharma and biotech companies battle to reduce research costs. These five AI players aim to crack the code. Computing speeds have exponentially improved over the past few decades and labs worldwide are increasingly equipped with tools…
Published on February 6, 2025
A highly virulent, and prevalent among birds, strain of avian flu has been detected in dairy cows in Nevada, according to the USDA Animal and Plant Health Inspection Service (APHIS). This has put public health officials on the alert as fear it could mutate and spread to more people. So…
Published on February 6, 2025
In New Brunswick, New Jersey, there is a lab where a robot performs microscopic operations on individual strands of hair of all types—curly, kinked, and straight—delicately splitting them open. Inside these thin, threadlike outgrowths, typically no thicker than 100 microns, lies a core containing a trove of biological information. According…
Published on February 5, 2025
New research from a team at The Hospital for Sick Children (SickKids) has identified a novel approach to combat a subtype of medulloblastoma, the most common malignant brain cancer in children. Published in Nature Communications, this research reveals a strategy that could transform the treatment of sonic hedgehog (SHH) medulloblastoma…
Published on February 5, 2025
Lung cancer in people who have never smoked is now estimated to be the fifth highest cause of cancer deaths worldwide. Lung cancer is still the leading cause of cancer incidence and mortality worldwide, with about 2.5 million people diagnosed with the disease in 2022 alone. But adenocarcinoma is now…
Published on February 4, 2025
Researchers based in Korea have built an artificial blood-brain barrier using specialized bioink and a 3D bioprinter, which they hope will help researchers to develop better treatments for brain-related disorders such as Alzheimer’s and Parkinson’s disease. The blood-brain barrier is a selective, semi-permeable membrane that lies between the brain and…
Published on February 4, 2025
Nearly 700,000 women across the U.K. will take part in a world-leading trial to test how cutting-edge AI tools can be used to catch breast cancer cases earlier, the U.K.’s Department of Health and Social Care announced today. That department is a division of the U.K.’s National Institute for Health…
Published on February 3, 2025
Atalanta Therapeutics has netted a $97 million Series B financing to support Phase I clinical trials of the company’s lead investigational RNAi therapies for KCNT1-related epilepsy and Huntington’s disease. This financing brings Atalanta’s total capital generated to-date from financings and partnerships to $262M. IND submissions are planned for 2025. The financing…
Published on February 3, 2025
The first oral medication of its kind, JOURNAVX™ (suzetrigine), has been approved by the U.S. Food and Drug Administration (FDA) to treat adults with moderate to severe acute pain. Created by Vertex Pharmaceuticals, JOURNAVX is a game-changer in pain treatment; it provides effective and well-tolerated pain relief without the dangers…
Published on January 31, 2025
Artificial intelligence (AI) can identify pregnancies that have a tenfold difference in the risk of poor outcomes but are currently treated equally under clinical guidelines. Using information on nearly 10,000 pregnancies, researchers developed an algorithm that could spot combinations of factors that led to poor outcomes such as still birth.…
Published on January 29, 2025
In a groundbreaking study, German researchers demonstrated the long-term safety and efficacy of tissue-engineered myocardial heart muscle (EHM) allografts and autografts in a clinically relevant rhesus macaque model, resulting in sustained remuscularization without harmful side effects, such as tumor formation or arrhythmia. These preclinical findings in non-human primates (NHPs) paved…
Published on January 29, 2025
Research led by The University of Texas MD Anderson Cancer Center has identified a novel first-line treatment regimen that combines chemotherapy with targeted therapy to improve response rates for people with difficult to treat BRAF V600E-mutant metastatic colorectal cancer (mCRC). The regimen involves concurrent chemotherapy with oxaliplatin, leucovorin, and 5-fluoruracil…
Published on January 29, 2025
Researchers at the Cleveland Clinic Genome Center (CCGC) have identified potential genetic factors that could play a role in Parkinson’s disease (PD), and have identified FDA-approved drugs that could be repurposed as new PD treatments. The research, published in the journal npj Parkinson’s Disease, used an artificial intelligence (AI) and…