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Published on April 25, 2024
People who take acid-reducing drugs to treat symptoms of acid reflux, may have a higher risk of migraine and other severe headache. The study, by researchers at the University of Maryland in College Park, was published yesterday in the online issue of Neurology Clinical Practice. Acid-reducing medications include proton pump…
Published on April 15, 2024
A recent analysis conducted by researchers at Georgetown University Medical Center says that one-third of 20 million women who answered a national health survey experienced migraines associated with menstruation and more than half (52.5%) were premenopausal. The findings, which will be presented Tuesday at the American Academy of Neurology 2024…
Published on March 29, 2022
Researchers from Brigham and Women’s Hospital and Massachusetts General Hospital have profiled, at single-cell resolution, the genes expressed in each trigeminal ganglion (TG) cell type. Their atlas may lead to the development of more effective treatments for migraine. Migraine and related headaches are caused by activity in the TG part…
Published on February 25, 2022
Results from a large preliminary study, that will be presented at the American Academy of Neurology’s 74th Annual Meeting, suggest that women with migraine have significantly increased risk for preterm delivery, pre-eclampsia and high blood pressure during pregnancy compared with women without migraine. Migraine, presenting as severe headaches with or…
Published on February 4, 2022
A large genome-wide association study including more than 800,000 people has revealed previously unknown genetic variants linked to migraine and identified targets that could be used to develop new treatments for this common condition. Although migraine, characterized by severe and recurring headaches, affects more than a billion people around the…
Published on December 16, 2021
Research from a large twin study carried out at the University of California (UC), San Diego suggests that the risk for developing migraine in later life is not entirely accounted for by genetic factors and may be linked to hormone exposure in the womb. Notably, the team also recorded differences…
Published on November 19, 2018
A drug previously approved for treating migraine and epilepsy has been found to slow the growth of triple negative breast cancer in mouse models. Researchers in the U.S., Taiwan, and China carried out screening studies to identify known pharmacologically active compounds that trigger degradation of N-Ras, a key protein that…
Published on May 4, 2018
Migraines often run in families, and although studies have implicated three particular genes in more severe, but uncommon, familial and sporadic forms of migraine, the genetic basis for the most types of migraine that run in families isn’t understood. Scientists in Finland and the U.S now report on an analysis…
Published on June 21, 2016
A team of researchers, all members of the International Headache Genetic Consortium, has uncovered 28 newly identified independent genomic regions associated with migraine by combining data from 22 genome-wide association studies that also included new data from approximately 35,000 migraine sufferers. The findings from this study were published recently in…
Published on April 10, 2024
Diagnostics company BillionToOne, a developer of liquid biopsy tests in oncology, will partner with Culmination Bio to validate two of its oncology diagnostic tests: Northstar Select, a test used to guide therapy selection; and Northstar Response which measures patient response to treatment. The deal, whose value was not disclosed, will…
Published on February 12, 2024
ol.custom-marker { counter-reset: list;}ol.custom-marker > li { list-style: none; counter-increment: list;}ol.custom-marker.parens-after.decimal > li::marker { content: counter(list) “)\a0”;} By Michael N. Liebman Biology embraces the existence of a central dogma, i.e., DNA → RNA → protein, and drug development has embraced its own, i.e., disease → target → drug, but both…
Published on July 21, 2023
University of Birmingham, England, researchers have launched a new study that will seek to develop a saliva-based early diagnostic for stroke. The research will build off past findings by Antonio Belli, MD, professor of Trauma Neurosurgery at the University of Birmingham’s Institute of Inflammation & Ageing, which could eventually dramatically…
Published on November 23, 2022
Artificial intelligence-driven remote health monitoring and digital health company Empatica announced on Tuesday that its Empatica Health Monitoring Platform was cleared by the U.S. Food and Drug Administration (FDA). The platform analyzes data from the company’s CE-certified EmbracePlus wearable which captures blood oxygen saturation (SpO2), peripheral skin temperature, activity associated…
Published on November 4, 2022
Researchers at University College London (UCL) have developed a new gene therapy approach for epilepsy and potentially other neurological and psychiatric diseases that works by reducing the excitability of overactive brain cells. The new closed-loop gene therapy approach enables the on-demand expression of a gene that tamps down the activity…
Published on September 8, 2022
New research from the University of Chicago (UChicago) that examine data from more than 400,000 people has provided new insights of the complex interaction between genetics and the environment in causing variability in common neuropsychiatric disorders. The investigators, whose findings were published in Cell Reports Medicine, are hopeful the information…