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Population-Wide Hereditary Breast, Ovarian Cancer Screening in Younger Women is Cost-Effective
The research suggests that wide screening of younger women for HBOC should be considered both to prevent more cancers and to help more women at low risk of breast cancer to avoid unnecessary additional screening.
Remote Screening Test for Ovarian Cancer Receives Study Validation
Between 2016 and 2020, a clinical trial engaged nearly 4,000 women from all 50 US states with the intention to validate different combinations of remote genetic counseling—the first large, randomized study of its kind to attempt to do so for cancer risk.
Ovarian Cancer Cells’ Dependence on Fat Suggests New Therapeutic Target
The enzyme Carnitine Palmitoyltransferase 1A (CPT1A) may control how much fat ovarian cancer cells can burn, suggesting a treatment that limits these cells’ access to CPT1A may starve them of the resources they need to spread.
Single-Cell Sequencing Provides Insights into Ovarian Cancer Subtypes
The scientists were able to identify new subtypes of normal fallopian tube cells. The molecular fingerprints of the subtypes that were identified had many genetic mirrors in individual ovarian cancers, which suggests that there may be many specific subtypes of ovarian cancer.
Myriad Wins Japanese Approval for BRACAnalysis to Assess Breast, Ovarian Cancer Risk
Diagnostic system tests for BRCA mutations in order to assess risk of Hereditary Breast and Ovarian Cancer (HBOC) syndrome in women with breast cancer.
FDA Approves Myriad’s myChoice CDx for Zejula’s Late-Line Ovarian Cancer Indication
The FDA has approved Myriad Genetics’ myChoice CDx as a companion diagnostic for Zejula (niraparib) to identify women with advanced ovarian cancer in the...
FoundationOne CDx Approved as Companion Diagnostic to Lynparza in Ovarian Cancer
The FDA has approved an expanded indication for Foundation Medicine’s FoundationOne®CDx, authorizing the test as a companion diagnostic for the AstraZeneca/Merck & Co. co-developed...
Ovarian Cancer Blood Test May Eliminate Need for Diagnostic Exploratory Surgery
Scientists at Uppsala University and the Sahlgrenska Academy, University of Gothenburg say they have developed a blood test that may provide a more precise...
Genetic Testing for Ovarian Cancer Patients is Underused
Patients with ovarian cancer are not getting all the testing they need, according to study a recently published in Journal of Clinical Oncology. Breast and...
Liquid Biopsies Provide Precision Approach to Ovarian Cancer Treatment
Scientists based at the University of Helsinki reported they were able to use the circulating tumor DNA shed by ovarian tumors to identify clinically actionable mutations and provide targeted treatments to patients.