Leukemia - search results

A team at the University of Virginia School of Medicine is leading an effort to create new therapeutic options for acute myeloid leukemia targeting a fusion protein involving the MLL protein fused with other proteins.

Researchers led by a team from the Netherlands have shown that adding the immunotherapy blinatumomab to chemotherapy delays progression and improves survival for infants with an aggressive type of acute lymphoblastic leukemia.

A novel combination therapy may treat a leukemia subtype harboring rearrangements in the KMT2A gene, which is more common in infants. The combination uses BET- and GSK3-inhibitors.

New findings have shown that contrary to previous belief, stems cells remain in the bone marrow in acute lymphocytic leukemia. The findings provide an explanation for why survivors experience negative effects on blood formation decades after they have been cured.

Syndax’s revumenib shows promise in advanced acute leukemias with KMT2A rearrangements or mutant NPM1, according to findings published this week in Nature.

Children with acute lymphoblastic leukemia (ALL) who lived along the Texas border with Mexico were more likely to die within five years than those living in other areas of the state.

A study by researchers at St. Jude Children’s Research Hospital delving into drug response across a swath of genetic subtypes of acute lymphoblastic leukemia (ALL), could provide a map for clinicians to more precisely match available treatments with a patient’s specific form of cancer.

A key inhibiting molecule called DUSP6, plays an important role in overcoming the resistance secondary acute myeloid leukemia often develops in response to treatment with drugs called JAK2 inhibitors.

A mathematical model may predict those patients with the blood cancer chronic myeloid leukemia who will best respond to treatment with tyrosine kinase inhibitors.

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