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Published on March 6, 2024
Researchers at Case Western Reserve University discovered that the ratio between two proteins, human beta defensin 3 (hBD‐3) and human beta defensin 2 (hBD‐2), is an early biomarker of oral cancer in suspicious oral cavity lesions. The team validated a new non-invasive oral cancer test based on the ratio of…
Published on December 14, 2022
A biosensor for oral cancer has been developed by researchers from the University of Florida and National Yang Ming Chiao Tung University in Taiwan. The device uses a rapid transistor-based system and is much faster and more convenient than current lab-based tests. Their study was published In Journal of Vacuum Science…
Published on June 19, 2017
MDxHealth and QUT bluebox, the commercialization arm of the Queensland University of Technology (QUT), said today they will partner to develop a liquid biopsy epigenetic assay designed for early detection of oral cancer. The value of the collaboration was not disclosed. The test will evaluate abnormal DNA methylation changes, an…
Published on September 15, 2023
Researchers at the German Cancer Research Center (DKFZ) have identified a membrane protein on the surface of cancer cells that supports and stabilizes an important factor involved in T-cell activation, thus potentially improving the anti-tumoral immune response. In recent years, Immune checkpoint inhibitors such as the anti-PD-L1 antibody nivolumab have…
Published on July 13, 2023
Scientists at Sylvester Comprehensive Cancer Center at the University of Miami Miller School of Medicine, have developed a first-of-its-kind, orally administered drug that can disrupt prostate cancer cell metabolism while simultaneously delivering the chemotherapy drug cisplatin directly into treatment-resistant prostate cancer cells. Cisplatin, a well established chemotherapy drug on the…
Published on January 4, 2023
Direct acting oral anticoagulants (DOACs) are more cost-effective than low molecular weight heparin (LMWH) injections for the treatment of cancer-associated thrombosis, shows a new study published in the Annals of Internal Medicine. The findings “should help policymakers and clinicians with decision-making,” when considering the most suitable treatment for these patients,…
Published on February 4, 2021
A new study in ovarian cancer found that using IgA-based antibodies produced by B cells may represent new immunotherapeutic agents for tumors resistant to conventional immune checkpoint blockade, which are currently focused on T cell-centric approaches. By design, immunotherapies are designed to boost the body’s T cells to recognize and…
Published on December 15, 2020
Researchers in the United States and China have recently released data from a study of the oral microbiome suggesting that the type and abundance of bacteria found in the mouth may be linked to lung cancer risk in nonsmokers. The study, which Albert Einstein College of Medicine assistant professor,…
Published on July 22, 2020
Virginia Tech researchers have discovered that a species of bacteria commonly found in the mouth can migrate around the body via the blood and trigger existing colorectal cancer cells (CRC) to spread, or metastasize. Studies have previously linked Fusobacterium nucleatum with colorectal tumors, increased tumor microenvironment inflammation, and poor patient prognosis. The…
Published on May 9, 2024
Applying three-dimensional AI to biopsies could predict the recurrence of prostate cancer better than traditional histopathology, researchers report. Their TriPath 3D pathology deep-learning platform more accurately reflected the intrinsically diverse nature of human tissue and could help guide clinical decisions, according to the findings reported in the journal Cell. The…
Published on May 1, 2024
Researchers at the University of Florida report they have developed an mRNA cancer vaccine that quickly reprograms the immune system to attack glioblastoma in a first-ever human clinical trial of four adult patients. Their results published in Cell mirror those from preclinical mouse studies, and from a newly reported trial…
Published on May 1, 2024
Cancer screening rates are significantly lower at Federally Qualified Health Centers (FQHCs) compared to overall national rates, according to a study published in JAMA Internal Medicine. The study found screening use in FQHCs was 45.4 percent for breast cancer, 51 percent for cervical cancer and 40.2 percent for colorectal cancer,…
Published on April 17, 2024
Scientists are seeking new ways to develop immunotherapies with different targets especially for patients with these cancers don’t respond to immune checkpoint inhibitors. Now, researchers from Osaka University report that tetracycline antibiotics help the immune system find cancer cells in a way that is different from current immunotherapies. The researchers…
Published on April 17, 2024
A recent discovery by researchers at the University of Arizona Medical School – Phoenix has shown that nanoparticle delivery of frizzled-4 (FZD4) to lung endothelial cells slows lung cancer progression and metastases. “We have identified the novel protein FOXF1 that stabilizes blood vessels inside the lung tumors, decreases intertumoral hypoxia…
Published on April 11, 2024
In a comprehensive study spanning three Scandinavian countries, researchers from the Karolinska Institute in Sweden have found no significant link between the use of GLP-1 analogues, a popular class of diabetes drugs, and an increased risk of thyroid cancer. Published in The BMJ, the study aims to put to rest…