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Gilead to Purchase Remaining Rights to Potential First-in-Class Immunotherapy from Jounce Therapeutics
Gilead Sciences and Jounce Therapeutics announced late Tuesday amendments to the existing terms and licensing agreements for GS-1811 (previously called JTX-1811), a potential first-in-class anti-CCR8 antibody in development as a potential treatment against solid tumors.
Reducing Hypoxia May Improve Immunotherapy
Tired T cells not only lose their own ability to fight cancer; they also influence surrounding cells to suppress an immune response.
Qu Biologics Taps Karolinska Institute to Validate Qu’s Immunotherapy Platform
The research will be led by Prof. Jonas Fuxe, and will characterize the molecular targets of Qu's Site Specific Immunomodulator (SSI) therapy at the tissue level that lead to resolution of disease.
Immunotherapy Plus Consolidation Chemo Improves Survival in B Lineage ALL
Adding the immunotherapy blinatumomab after an initial round of consolidation chemotherapy in patients with good prognosis with B lineage acute lymphoblastic leukemia (ALL) kept most patients in remission and improved survival.
Gene Variant Flags Immunotherapy Issues
Researchers have made important progress in identifying skin cancer patients who are genetically at high risk of side effects from immunotherapy.
Aneuploidy Revealed as a Key Biomarker in Cancer Immunotherapy and Radiation Response
Scientists at the University of Chicago discovered that lung cancers with high aneuploidy responded better to simultaneous treatment with radiation and immunotherapy.
CD8+ T-Cell Infiltration Level Linked to Cancer Immunotherapy Response
Cancer patients’ response to immunotherapy may be predictable in part based on their levels of CD8+ T cell infiltration.
Dual-Action Nanoparticles Deliver Chemoimmunotherapy
Researchers from the University of Pittsburgh have developed a new cancer treatment strategy involving co-delivery of a chemotherapy drug and a newly identified immunotherapy.
Biomarkers Found for Hyper-Progression of Melanoma after Immunotherapy
Certain biomarkers may predict likelihood of checkpoint inhibitor drugs "backfiring" during melanoma treatment. Duke Cancer Institute researchers have identified a pathway that may explain why this serious side effect occurs in a subset of patients.
Deep Learning Predicts Immunotherapy Response
A deep learning model helps reveal the immune system's response to immunotherapy. The model may even pave the way for treatment approaches for diseases outside of oncology.